Lack of prion accumulation in lymphoid tissues of PRNP ARQ/ARR sheep intracranially inoculated with the agent of scrapie.

Lack of prion accumulation in lymphoid tissues of PRNP ARQ/ARR sheep intracranially inoculated with the agent of scrapie.

Sheep scrapie is a transmissible spongiform encephalopathy that can be transmitted horizontally. The prion protein gene (PRNP) profoundly influences the susceptibility of sheep to the scrapie agent and the tissue levels and distribution of PrPSc in affected sheep. The purpose of this study was to co...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy:	Justin J Greenlee, Robert A Kunkle, Jürgen A Richt, Eric M Nicholson, Amir N Hamir
Format:	Artykuł
Język:	English
Wydane:	Public Library of Science (PLoS) 2014-01-01
Seria:	PLoS ONE
Dostęp online:	http://europepmc.org/articles/PMC4169493?pdf=render

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