Vascular injury of immature epiphyses impair stem cell engraftment in cartilage defects

Abstract The purpose of our study was to investigate if vascular injury in immature epiphyses affects cartilage repair outcomes of matrix-associated stem cell implants (MASI). Porcine bone marrow mesenchymal stromal stem cells (BMSCs) suspended in a fibrin glue scaffold were implanted into 24 full-t...

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Main Authors: Ali Rashidi, Ashok J. Theruvath, Ching-Hsin Huang, Wei Wu, Elhussein E. Mahmoud, Joe Gerald Jesu Raj, Krzysztof Marycz, Heike E. Daldrup-Link
Format: Article
Jezik:English
Izdano: Nature Portfolio 2022-07-01
Serija:Scientific Reports
Online dostop:https://doi.org/10.1038/s41598-022-15721-6