Sympathetic activity and arterial hypertension: potential for correction

The paper is focussed on the role of increased sympathetic activation in the pathogenesis of arterial hypertension (AH), its exacerbations (hypertensive crises), and complications. One of the effective methods of interrupting pathogenetic “vicious circles” in AH is the blockage of peripheral alpha-a...

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Main Authors: O. Yu. Shayduk, E. O. Taratukhin
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2013-04-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/365
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author O. Yu. Shayduk
E. O. Taratukhin
author_facet O. Yu. Shayduk
E. O. Taratukhin
author_sort O. Yu. Shayduk
collection DOAJ
description The paper is focussed on the role of increased sympathetic activation in the pathogenesis of arterial hypertension (AH), its exacerbations (hypertensive crises), and complications. One of the effective methods of interrupting pathogenetic “vicious circles” in AH is the blockage of peripheral alpha-adrenoreceptors. One of the medications of choice for urgent treatment of hypertensive crises, as well as for long-term ambulatory treatment, is urapidil – a peripheral sympatholytic with characteristics of a central serotonin receptor agonist.
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spelling doaj.art-f8501aa583684419a2a4ce449abb18982023-03-29T21:23:20Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202013-04-0102616410.15829/1560-4071-2013-2-61-64365Sympathetic activity and arterial hypertension: potential for correctionO. Yu. Shayduk0E. O. Taratukhin1Hospital Therapy Department No. 1, Therapy Faculty, N. I. Pirogov National Medical Research University, Moscow, RussiaHospital Therapy Department No. 1, Therapy Faculty, N. I. Pirogov National Medical Research University, Moscow, RussiaThe paper is focussed on the role of increased sympathetic activation in the pathogenesis of arterial hypertension (AH), its exacerbations (hypertensive crises), and complications. One of the effective methods of interrupting pathogenetic “vicious circles” in AH is the blockage of peripheral alpha-adrenoreceptors. One of the medications of choice for urgent treatment of hypertensive crises, as well as for long-term ambulatory treatment, is urapidil – a peripheral sympatholytic with characteristics of a central serotonin receptor agonist.https://russjcardiol.elpub.ru/jour/article/view/365catecholaminesurapidiladrenoreceptorssleep apnoea
spellingShingle O. Yu. Shayduk
E. O. Taratukhin
Sympathetic activity and arterial hypertension: potential for correction
Российский кардиологический журнал
catecholamines
urapidil
adrenoreceptors
sleep apnoea
title Sympathetic activity and arterial hypertension: potential for correction
title_full Sympathetic activity and arterial hypertension: potential for correction
title_fullStr Sympathetic activity and arterial hypertension: potential for correction
title_full_unstemmed Sympathetic activity and arterial hypertension: potential for correction
title_short Sympathetic activity and arterial hypertension: potential for correction
title_sort sympathetic activity and arterial hypertension potential for correction
topic catecholamines
urapidil
adrenoreceptors
sleep apnoea
url https://russjcardiol.elpub.ru/jour/article/view/365
work_keys_str_mv AT oyushayduk sympatheticactivityandarterialhypertensionpotentialforcorrection
AT eotaratukhin sympatheticactivityandarterialhypertensionpotentialforcorrection