LncRNA-H19 Drives Cardiomyocyte Senescence by Targeting miR-19a/socs1/p53 Axis

LncRNA-H19 Drives Cardiomyocyte Senescence by Targeting miR-19a/socs1/p53 Axis

Purpose: Cardiomyocyte senescence is associated with a progressive decline in cardiac physiological function and the risk of cardiovascular events. lncRNA H19 (H19), a well-known long noncoding RNA (lncRNA), is involved in the pathophysiological process of multiple cardiovascular disease such as hea...

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Bibliographic Details
Main Authors: Yuting Zhuang, Tingting Li, Hongwen Xiao, Jiaxu Wu, Shuang Su, Xue Dong, Xiaoxi Hu, Qi Hua, Junwu Liu, Wendi Shang, Jiaming Ju, Fei Sun, Zhenwei Pan, Yanjie Lu, Mingyu Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Pharmacology
Subjects:
p53
SOCS1
miR-19
cardiomyocyte senescence
H19
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.631835/full

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