Accuracy of small and medium field of view CBCT in differentiation between periapical cystic and solid lesions

Objective: The aim of this study is to determine if small and medium field of view (FOV) cone beam computed tomography (CBCT) adjusted grey density values can be used to distinguish between periapical cystic and solid lesions. Materials and methods: Fifty-one patients with periapical lesions having...

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Main Authors: Dania AlMadi, Malak Al-Hadlaq, Ohoud AlOtaibi, Asma'a Al-Ekrish
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Saudi Dental Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1013905219300094
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author Dania AlMadi
Malak Al-Hadlaq
Ohoud AlOtaibi
Asma'a Al-Ekrish
author_facet Dania AlMadi
Malak Al-Hadlaq
Ohoud AlOtaibi
Asma'a Al-Ekrish
author_sort Dania AlMadi
collection DOAJ
description Objective: The aim of this study is to determine if small and medium field of view (FOV) cone beam computed tomography (CBCT) adjusted grey density values can be used to distinguish between periapical cystic and solid lesions. Materials and methods: Fifty-one patients with periapical lesions having retrievable small or medium FOV CBCT images and biopsy samples were included in the study. Two oral and maxillofacial pathologists diagnosed the biopsy samples to provide the gold standard diagnosis of cystic or solid lesion. From the CBCT images, two independent examiners recorded the minimum adjusted grey density value of each lesion twice. Intra-examiner and inter-examiner reliability of the measurements were analyzed, and the sensitivity, specificity, and accuracy of the minimum grey values in distinguishing a solid from cystic lesion were calculated. An ROC curve for diagnostic ability of adjusted grey density values to differentiate between periapical cystic and solid lesions was obtained and the area under the curve (AUC) was calculated. Results: The intra-examiner and inter-examiner reliability, demonstrated as the intraclass correlation coefficient of the lesion’s and dentin’s grey density values were excellent. The mean ± standard deviation of the sensitivity and specificity were determined as 0.53 ± 0.28 and 0.52 ± 0.31, respectively. The AUC was found to be 0.55 (P-value = 0.57). Conclusion: Small and medium field of view CBCT adjusted grey density values obtained by the device used in the study could not be used to distinguish between periapical cystic and solid lesions. Further developments in CBCT devices are needed to improve the accuracy of grey density measurements.
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spelling doaj.art-f8564076a93e49918ebabc83724082ac2022-12-21T22:40:56ZengElsevierSaudi Dental Journal1013-90522019-01-0131S3Accuracy of small and medium field of view CBCT in differentiation between periapical cystic and solid lesionsDania AlMadi0Malak Al-Hadlaq1Ohoud AlOtaibi2Asma'a Al-Ekrish3College of Dentistry, King Saud University, Saudi ArabiaDepartment of Oral Medicine and Diagnostics Sciences, College of Dentistry, King Saud University, Saudi ArabiaDepartment of Oral Medicine and Diagnostics Sciences, College of Dentistry, King Saud University, Saudi ArabiaDivision of Oral and Maxillofacial Radiology, Department of Oral Medicine and Diagnostic Sciences, College of Dentistry, King Saud University, Saudi ArabiaObjective: The aim of this study is to determine if small and medium field of view (FOV) cone beam computed tomography (CBCT) adjusted grey density values can be used to distinguish between periapical cystic and solid lesions. Materials and methods: Fifty-one patients with periapical lesions having retrievable small or medium FOV CBCT images and biopsy samples were included in the study. Two oral and maxillofacial pathologists diagnosed the biopsy samples to provide the gold standard diagnosis of cystic or solid lesion. From the CBCT images, two independent examiners recorded the minimum adjusted grey density value of each lesion twice. Intra-examiner and inter-examiner reliability of the measurements were analyzed, and the sensitivity, specificity, and accuracy of the minimum grey values in distinguishing a solid from cystic lesion were calculated. An ROC curve for diagnostic ability of adjusted grey density values to differentiate between periapical cystic and solid lesions was obtained and the area under the curve (AUC) was calculated. Results: The intra-examiner and inter-examiner reliability, demonstrated as the intraclass correlation coefficient of the lesion’s and dentin’s grey density values were excellent. The mean ± standard deviation of the sensitivity and specificity were determined as 0.53 ± 0.28 and 0.52 ± 0.31, respectively. The AUC was found to be 0.55 (P-value = 0.57). Conclusion: Small and medium field of view CBCT adjusted grey density values obtained by the device used in the study could not be used to distinguish between periapical cystic and solid lesions. Further developments in CBCT devices are needed to improve the accuracy of grey density measurements.http://www.sciencedirect.com/science/article/pii/S1013905219300094
spellingShingle Dania AlMadi
Malak Al-Hadlaq
Ohoud AlOtaibi
Asma'a Al-Ekrish
Accuracy of small and medium field of view CBCT in differentiation between periapical cystic and solid lesions
Saudi Dental Journal
title Accuracy of small and medium field of view CBCT in differentiation between periapical cystic and solid lesions
title_full Accuracy of small and medium field of view CBCT in differentiation between periapical cystic and solid lesions
title_fullStr Accuracy of small and medium field of view CBCT in differentiation between periapical cystic and solid lesions
title_full_unstemmed Accuracy of small and medium field of view CBCT in differentiation between periapical cystic and solid lesions
title_short Accuracy of small and medium field of view CBCT in differentiation between periapical cystic and solid lesions
title_sort accuracy of small and medium field of view cbct in differentiation between periapical cystic and solid lesions
url http://www.sciencedirect.com/science/article/pii/S1013905219300094
work_keys_str_mv AT daniaalmadi accuracyofsmallandmediumfieldofviewcbctindifferentiationbetweenperiapicalcysticandsolidlesions
AT malakalhadlaq accuracyofsmallandmediumfieldofviewcbctindifferentiationbetweenperiapicalcysticandsolidlesions
AT ohoudalotaibi accuracyofsmallandmediumfieldofviewcbctindifferentiationbetweenperiapicalcysticandsolidlesions
AT asmaaalekrish accuracyofsmallandmediumfieldofviewcbctindifferentiationbetweenperiapicalcysticandsolidlesions