Case Report: Recurrent meningioma with multiple metastases
Post-surgery recurrence of meningiomas with multiple extracranial metastases is rare. Currently, information on extracranial metastases is limited, and no clear predictors and standardized treatment protocols can be applied clinically. Herein, we report a case of meningioma that recurred after two s...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-07-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1192575/full |
| _version_ | 1797778280328200192 |
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| author | Juyue Zhou Juyue Zhou Zhonghai Du |
| author_facet | Juyue Zhou Juyue Zhou Zhonghai Du |
| author_sort | Juyue Zhou |
| collection | DOAJ |
| description | Post-surgery recurrence of meningiomas with multiple extracranial metastases is rare. Currently, information on extracranial metastases is limited, and no clear predictors and standardized treatment protocols can be applied clinically. Herein, we report a case of meningioma that recurred after two surgeries and had multiple distant metastases. Computed tomography revealed multiple enlarged lymph nodes in the para-aortic arch, left lower lung region, retroperitoneum, and abdominopelvic region, as well as soft tissue mass-like lesions under the liver capsule in the right lobe of the liver. Magnetic resonance imaging showed space-occupying lesions under the cranial plate of the left parietal lobe. Tissue biopsy confirmed the diagnosis of recurrent meningioma with extracranial metastases. Immune checkpoint inhibitors and anti-angiogenic drugs were administered. After two treatment cycles, the patient’s clinical symptoms were significantly relieved, and the imaging assessment confirmed a stable disease. Although it did not meet our expectations, this combination therapy still demonstrated a possible benefit in improving meningioma patients’ survival and quality of life. In this report, along with the case, we also review the relevant literature on the subject and discuss the associated risk factors and treatment options. |
| first_indexed | 2024-03-12T23:15:00Z |
| format | Article |
| id | doaj.art-f85a31b95b174d75a44864daac8a0227 |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-03-12T23:15:00Z |
| publishDate | 2023-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-f85a31b95b174d75a44864daac8a02272023-07-17T13:04:04ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-07-011310.3389/fonc.2023.11925751192575Case Report: Recurrent meningioma with multiple metastasesJuyue Zhou0Juyue Zhou1Zhonghai Du2Graduate Institute, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, ChinaDepartment of Oncology, Weifang Hospital of Traditional Chinese Medicine, Weifang, Shandong, ChinaDepartment of Oncology, Weifang Hospital of Traditional Chinese Medicine, Weifang, Shandong, ChinaPost-surgery recurrence of meningiomas with multiple extracranial metastases is rare. Currently, information on extracranial metastases is limited, and no clear predictors and standardized treatment protocols can be applied clinically. Herein, we report a case of meningioma that recurred after two surgeries and had multiple distant metastases. Computed tomography revealed multiple enlarged lymph nodes in the para-aortic arch, left lower lung region, retroperitoneum, and abdominopelvic region, as well as soft tissue mass-like lesions under the liver capsule in the right lobe of the liver. Magnetic resonance imaging showed space-occupying lesions under the cranial plate of the left parietal lobe. Tissue biopsy confirmed the diagnosis of recurrent meningioma with extracranial metastases. Immune checkpoint inhibitors and anti-angiogenic drugs were administered. After two treatment cycles, the patient’s clinical symptoms were significantly relieved, and the imaging assessment confirmed a stable disease. Although it did not meet our expectations, this combination therapy still demonstrated a possible benefit in improving meningioma patients’ survival and quality of life. In this report, along with the case, we also review the relevant literature on the subject and discuss the associated risk factors and treatment options.https://www.frontiersin.org/articles/10.3389/fonc.2023.1192575/fullcase reportmeningiomarecurrenceaggressivenessextracranial metastasis |
| spellingShingle | Juyue Zhou Juyue Zhou Zhonghai Du Case Report: Recurrent meningioma with multiple metastases Frontiers in Oncology case report meningioma recurrence aggressiveness extracranial metastasis |
| title | Case Report: Recurrent meningioma with multiple metastases |
| title_full | Case Report: Recurrent meningioma with multiple metastases |
| title_fullStr | Case Report: Recurrent meningioma with multiple metastases |
| title_full_unstemmed | Case Report: Recurrent meningioma with multiple metastases |
| title_short | Case Report: Recurrent meningioma with multiple metastases |
| title_sort | case report recurrent meningioma with multiple metastases |
| topic | case report meningioma recurrence aggressiveness extracranial metastasis |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2023.1192575/full |
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