Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects

<p>We study the osteoinductive effect of the hyaluronic acid (HA) by using an esterified low-molecular HA preparation (EHA) as a coadjuvant in the grafting processes to produce bone-like tissue in the presence of employing autologous bone obtained from intra-oral sites, to treat infra-bone def...

Full description

Bibliographic Details
Main Author: Andrea BALLINI, Stefania CANTORE, Saverio CAPODIFERRO, Felice Roberto GRASSI
Format: Article
Language:English
Published: Ivyspring International Publisher 2009-01-01
Series:International Journal of Medical Sciences
Online Access:http://www.medsci.org/v06p0065.htm
_version_ 1818062335073320960
author Andrea BALLINI, Stefania CANTORE, Saverio CAPODIFERRO, Felice Roberto GRASSI
author_facet Andrea BALLINI, Stefania CANTORE, Saverio CAPODIFERRO, Felice Roberto GRASSI
author_sort Andrea BALLINI, Stefania CANTORE, Saverio CAPODIFERRO, Felice Roberto GRASSI
collection DOAJ
description <p>We study the osteoinductive effect of the hyaluronic acid (HA) by using an esterified low-molecular HA preparation (EHA) as a coadjuvant in the grafting processes to produce bone-like tissue in the presence of employing autologous bone obtained from intra-oral sites, to treat infra-bone defects without covering membrane.</p> <p>We report on 9 patients with periodontal defects treated by EHA and autologous grafting (4 males and 5 females, all non smokers, with a mean age of 43,8 years for females, 40,0 years for males and 42 years for all the group, in good health) with a mean depth of 8.3 mm of the infra-bone defects, as revealed by intra-operative probes. Data were obtained at baseline before treatment and after 10 days, and subsequently at 6,9, and 24 months after treatment.</p> <p>Clinical results showed a mean gain hi clinical attachment (<i>gCAL)</i> of 2.6mm of the treated sites, confirmed by radiographic evaluation. Such results suggest that autologous bone combined with EHA seems to have good capabilities in accelerating new bone formation in the infra-bone defects.</p>
first_indexed 2024-12-10T14:02:34Z
format Article
id doaj.art-f85af20c035c417592f4d0369c22537a
institution Directory Open Access Journal
issn 1449-1907
language English
last_indexed 2024-12-10T14:02:34Z
publishDate 2009-01-01
publisher Ivyspring International Publisher
record_format Article
series International Journal of Medical Sciences
spelling doaj.art-f85af20c035c417592f4d0369c22537a2022-12-22T01:45:45ZengIvyspring International PublisherInternational Journal of Medical Sciences1449-19072009-01-01626571Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone DefectsAndrea BALLINI, Stefania CANTORE, Saverio CAPODIFERRO, Felice Roberto GRASSI<p>We study the osteoinductive effect of the hyaluronic acid (HA) by using an esterified low-molecular HA preparation (EHA) as a coadjuvant in the grafting processes to produce bone-like tissue in the presence of employing autologous bone obtained from intra-oral sites, to treat infra-bone defects without covering membrane.</p> <p>We report on 9 patients with periodontal defects treated by EHA and autologous grafting (4 males and 5 females, all non smokers, with a mean age of 43,8 years for females, 40,0 years for males and 42 years for all the group, in good health) with a mean depth of 8.3 mm of the infra-bone defects, as revealed by intra-operative probes. Data were obtained at baseline before treatment and after 10 days, and subsequently at 6,9, and 24 months after treatment.</p> <p>Clinical results showed a mean gain hi clinical attachment (<i>gCAL)</i> of 2.6mm of the treated sites, confirmed by radiographic evaluation. Such results suggest that autologous bone combined with EHA seems to have good capabilities in accelerating new bone formation in the infra-bone defects.</p>http://www.medsci.org/v06p0065.htm
spellingShingle Andrea BALLINI, Stefania CANTORE, Saverio CAPODIFERRO, Felice Roberto GRASSI
Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects
International Journal of Medical Sciences
title Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects
title_full Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects
title_fullStr Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects
title_full_unstemmed Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects
title_short Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects
title_sort esterified hyaluronic acid and autologous bone in the surgical correction of the infra bone defects
url http://www.medsci.org/v06p0065.htm
work_keys_str_mv AT andreaballinistefaniacantoresaveriocapodiferrofelicerobertograssi esterifiedhyaluronicacidandautologousboneinthesurgicalcorrectionoftheinfrabonedefects