Person-centered and measured life’s simple 7 cardiovascular health concordance and association with incident cardiovascular disease
Abstract Person-centered cardiovascular health (CVH) may facilitate cardiovascular disease primordial prevention in low resources settings. The study aims to assess the validity of person-centered CVH compared to gold standard measured CVH by examining the concordance between person-centered vs. mea...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-03-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-32219-x |
| _version_ | 1797853891271852032 |
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| author | Omar Deraz Thomas Van Sloten Rachel Climie Charlotte Debras Léopold K. Fezeu Mélanie Deschasaux-Tanguy Xavier Jouven Emmanuelle Kesse-Guyot Pilar Galan Serge Hercberg Mathilde Touvier Jean-Philippe Empana |
| author_facet | Omar Deraz Thomas Van Sloten Rachel Climie Charlotte Debras Léopold K. Fezeu Mélanie Deschasaux-Tanguy Xavier Jouven Emmanuelle Kesse-Guyot Pilar Galan Serge Hercberg Mathilde Touvier Jean-Philippe Empana |
| author_sort | Omar Deraz |
| collection | DOAJ |
| description | Abstract Person-centered cardiovascular health (CVH) may facilitate cardiovascular disease primordial prevention in low resources settings. The study aims to assess the validity of person-centered CVH compared to gold standard measured CVH by examining the concordance between person-centered vs. measured CVH together with their respective association with incident cardiovascular disease events (CVD). Life’s Simple 7 (LS7) CVH metrics, including non-smoking, Body Mass Index, diet, physical activity, blood glycemia, blood pressure, and blood cholesterol were collected from 19,473 adults participating in the e-cohort NutriNet-Santé study from 2011 to 2014 and were followed until September 2020. Clinical examinations and blood analyses defined the measured biological metrics, while diagnoses, medication, or treatment for type 2 diabetes, hypertension, and hypercholesterolemia defined person-centered biological metrics. Declared behavioral metrics were common for both measured and person-centered CVH. The study included 18,714 CVD-free participants (mean age 51 years, 73% women), among whom 16.52% and 38.75% had 5–7 ideal LS7 metrics according to measured and person-centered CVH, respectively. Weighted concordance of person-centered and measured CVH was 0.87 [0.86; 0.88]. Over median follow-up of 8.05 years, 749 CVD events occurred. There was a 7% (HR 0.93 [0.88; 0.99]) and 13% (HR 0.87 [0.83; 0.92]) risk reduction of CVD risk by additional measured and person-centered ideal metrics, respectively. In conclusion, person-centered CVH may represent a reliable alternative to measured CVH. |
| first_indexed | 2024-04-09T19:58:08Z |
| format | Article |
| id | doaj.art-f8636a46969a4be1a977453185f5edcf |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-09T19:58:08Z |
| publishDate | 2023-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-f8636a46969a4be1a977453185f5edcf2023-04-03T05:24:12ZengNature PortfolioScientific Reports2045-23222023-03-0113111210.1038/s41598-023-32219-xPerson-centered and measured life’s simple 7 cardiovascular health concordance and association with incident cardiovascular diseaseOmar Deraz0Thomas Van Sloten1Rachel Climie2Charlotte Debras3Léopold K. Fezeu4Mélanie Deschasaux-Tanguy5Xavier Jouven6Emmanuelle Kesse-Guyot7Pilar Galan8Serge Hercberg9Mathilde Touvier10Jean-Philippe Empana11Université Paris Cité, UMR-S970, Paris Cardiovascular Research Center, INSERM, Integrative Epidemiology of Cardiovascular Disease (Team 4)Université Paris Cité, UMR-S970, Paris Cardiovascular Research Center, INSERM, Integrative Epidemiology of Cardiovascular Disease (Team 4)Université Paris Cité, UMR-S970, Paris Cardiovascular Research Center, INSERM, Integrative Epidemiology of Cardiovascular Disease (Team 4)Nutritional Epidemiology Research Team (EREN), Sorbonne Paris Nord University, Inserm U1153, Inrae U1125, Cnam, Epidemiology and Statistics Research Center – University of Paris (CRESS)Nutritional Epidemiology Research Team (EREN), Sorbonne Paris Nord University, Inserm U1153, Inrae U1125, Cnam, Epidemiology and Statistics Research Center – University of Paris (CRESS)Nutritional Epidemiology Research Team (EREN), Sorbonne Paris Nord University, Inserm U1153, Inrae U1125, Cnam, Epidemiology and Statistics Research Center – University of Paris (CRESS)Université Paris Cité, UMR-S970, Paris Cardiovascular Research Center, INSERM, Integrative Epidemiology of Cardiovascular Disease (Team 4)Nutritional Epidemiology Research Team (EREN), Sorbonne Paris Nord University, Inserm U1153, Inrae U1125, Cnam, Epidemiology and Statistics Research Center – University of Paris (CRESS)Nutritional Epidemiology Research Team (EREN), Sorbonne Paris Nord University, Inserm U1153, Inrae U1125, Cnam, Epidemiology and Statistics Research Center – University of Paris (CRESS)Nutritional Epidemiology Research Team (EREN), Sorbonne Paris Nord University, Inserm U1153, Inrae U1125, Cnam, Epidemiology and Statistics Research Center – University of Paris (CRESS)Nutritional Epidemiology Research Team (EREN), Sorbonne Paris Nord University, Inserm U1153, Inrae U1125, Cnam, Epidemiology and Statistics Research Center – University of Paris (CRESS)Université Paris Cité, UMR-S970, Paris Cardiovascular Research Center, INSERM, Integrative Epidemiology of Cardiovascular Disease (Team 4)Abstract Person-centered cardiovascular health (CVH) may facilitate cardiovascular disease primordial prevention in low resources settings. The study aims to assess the validity of person-centered CVH compared to gold standard measured CVH by examining the concordance between person-centered vs. measured CVH together with their respective association with incident cardiovascular disease events (CVD). Life’s Simple 7 (LS7) CVH metrics, including non-smoking, Body Mass Index, diet, physical activity, blood glycemia, blood pressure, and blood cholesterol were collected from 19,473 adults participating in the e-cohort NutriNet-Santé study from 2011 to 2014 and were followed until September 2020. Clinical examinations and blood analyses defined the measured biological metrics, while diagnoses, medication, or treatment for type 2 diabetes, hypertension, and hypercholesterolemia defined person-centered biological metrics. Declared behavioral metrics were common for both measured and person-centered CVH. The study included 18,714 CVD-free participants (mean age 51 years, 73% women), among whom 16.52% and 38.75% had 5–7 ideal LS7 metrics according to measured and person-centered CVH, respectively. Weighted concordance of person-centered and measured CVH was 0.87 [0.86; 0.88]. Over median follow-up of 8.05 years, 749 CVD events occurred. There was a 7% (HR 0.93 [0.88; 0.99]) and 13% (HR 0.87 [0.83; 0.92]) risk reduction of CVD risk by additional measured and person-centered ideal metrics, respectively. In conclusion, person-centered CVH may represent a reliable alternative to measured CVH.https://doi.org/10.1038/s41598-023-32219-x |
| spellingShingle | Omar Deraz Thomas Van Sloten Rachel Climie Charlotte Debras Léopold K. Fezeu Mélanie Deschasaux-Tanguy Xavier Jouven Emmanuelle Kesse-Guyot Pilar Galan Serge Hercberg Mathilde Touvier Jean-Philippe Empana Person-centered and measured life’s simple 7 cardiovascular health concordance and association with incident cardiovascular disease Scientific Reports |
| title | Person-centered and measured life’s simple 7 cardiovascular health concordance and association with incident cardiovascular disease |
| title_full | Person-centered and measured life’s simple 7 cardiovascular health concordance and association with incident cardiovascular disease |
| title_fullStr | Person-centered and measured life’s simple 7 cardiovascular health concordance and association with incident cardiovascular disease |
| title_full_unstemmed | Person-centered and measured life’s simple 7 cardiovascular health concordance and association with incident cardiovascular disease |
| title_short | Person-centered and measured life’s simple 7 cardiovascular health concordance and association with incident cardiovascular disease |
| title_sort | person centered and measured life s simple 7 cardiovascular health concordance and association with incident cardiovascular disease |
| url | https://doi.org/10.1038/s41598-023-32219-x |
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