Role for Gag-CA Interdomain Linker in Primate Lentiviral Replication

Role for Gag-CA Interdomain Linker in Primate Lentiviral Replication

Gag proteins underlie retroviral replication by fulfilling numerous functional roles at various stages during viral life cycle. Out of the four mature proteins, Gag-capsid (CA) is a major component of viral particles, and has been most well studied biogenetically, biochemically and structurally. Gag...

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Bibliographic Details
Main Authors: Naoya Doi, Takaaki Koma, Akio Adachi, Masako Nomaguchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Microbiology
Subjects:
HIV/SIV
Gag-CA
interdomain linker
Gag assembly
virus production
early infectivity
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01831/full

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