Understanding tumor localization in multiparametric MRI of the prostate—effectiveness of 3D printed models
IntroductionUnderstanding tumor localization in multiparametric MRI (mpMRI) of the prostate is challenging for urologists but of great importance in mpMRI-fused prostate biopsy or radical prostatectomy. The aim was to evaluate the effectiveness of 3D printed models of the prostate to help urologists...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-09-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2023.1264164/full |
| _version_ | 1797679334091128832 |
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| author | Maximilian Haack Katja Reisen Ahmed Ghazy Kristina Stroh Lisa Frey Peter Sparwasser Gregor Duwe Rene Mager Axel Haferkamp Hendrik Borgmann Hendrik Borgmann |
| author_facet | Maximilian Haack Katja Reisen Ahmed Ghazy Kristina Stroh Lisa Frey Peter Sparwasser Gregor Duwe Rene Mager Axel Haferkamp Hendrik Borgmann Hendrik Borgmann |
| author_sort | Maximilian Haack |
| collection | DOAJ |
| description | IntroductionUnderstanding tumor localization in multiparametric MRI (mpMRI) of the prostate is challenging for urologists but of great importance in mpMRI-fused prostate biopsy or radical prostatectomy. The aim was to evaluate the effectiveness of 3D printed models of the prostate to help urologists to locate tumors.Methods and Participants20 urologists from University Medical Center Mainz (Germany) were asked to plot the location of a cancer suspicious lesion (PI-RADS ≥ 4) on a total of 30 mpMRI on a prostate sector diagram. The following 3 groups (as matched triplets) were divided into: mpMRI only, mpMRI with radiological report and mpMRI with 3D printed model (scaled 1:1). Statistical analysis was performed using one-way and two-way ANOVA (with bonferroni post-test).ResultsOverall, localization of the suspicious lesion was superior with the radiological report (median of max. 10 [IQR]: MRI 2 [IQR 1;5], MRI + report: 8 [6.3;9], MRI + 3D model 3 [1.3;5.8]; p < 0.001). Residents with <1 year of experience had a significantly higher detection rate using a 3D printed model [5 (5;5.8)] compared to mpMRI alone [1.5 (1;3.5)] (p < 0.05). Regarding the estimation of index lesion extension, the 3D model showed a significant benefit (mean percentage difference [95% CI]: MRI alone 234% [17.1;451.5], MRI + report 114% [78.5;149.6], MRI + 3D model 17% [−7.4;41.3] (p < 0.01).ConclusionUrologists still need the written radiological report for a sufficient understanding of tumor localization. The effectiveness of the 3D printed model regarding tumor localization is particularly evident in young residents (<1 year) and leads to a better overall assessment of the tumor extension. |
| first_indexed | 2024-03-11T23:13:01Z |
| format | Article |
| id | doaj.art-f86e71fcc017454680d02789d5ba93a1 |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-03-11T23:13:01Z |
| publishDate | 2023-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj.art-f86e71fcc017454680d02789d5ba93a12023-09-21T07:25:56ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2023-09-011010.3389/fsurg.2023.12641641264164Understanding tumor localization in multiparametric MRI of the prostate—effectiveness of 3D printed modelsMaximilian Haack0Katja Reisen1Ahmed Ghazy2Kristina Stroh3Lisa Frey4Peter Sparwasser5Gregor Duwe6Rene Mager7Axel Haferkamp8Hendrik Borgmann9Hendrik Borgmann10Department of Urology and Pediatric Urology, Johannes-Gutenberg-University Medical Center, Mainz, GermanyDepartment of Urology and Pediatric Urology, Johannes-Gutenberg-University Medical Center, Mainz, GermanyDepartment of Cardiovascular Surgery, Johannes-Gutenberg-University Medical Center, Mainz, GermanyDepartment of Diagnostic and Interventional Radiology, Johannes-Gutenberg-University Medical Center, Mainz, GermanyDepartment of Urology and Pediatric Urology, Johannes-Gutenberg-University Medical Center, Mainz, GermanyDepartment of Urology and Pediatric Urology, Johannes-Gutenberg-University Medical Center, Mainz, GermanyDepartment of Urology and Pediatric Urology, Johannes-Gutenberg-University Medical Center, Mainz, GermanyDepartment of Urology and Pediatric Urology, Johannes-Gutenberg-University Medical Center, Mainz, GermanyDepartment of Urology and Pediatric Urology, Johannes-Gutenberg-University Medical Center, Mainz, GermanyDepartment of Urology and Pediatric Urology, Johannes-Gutenberg-University Medical Center, Mainz, GermanyDepartment of Urology, Faculty of Health Sciences Brandenburg, Brandenburg Medical School Theodor Fontane, Brandenburg an der Havel, GermanyIntroductionUnderstanding tumor localization in multiparametric MRI (mpMRI) of the prostate is challenging for urologists but of great importance in mpMRI-fused prostate biopsy or radical prostatectomy. The aim was to evaluate the effectiveness of 3D printed models of the prostate to help urologists to locate tumors.Methods and Participants20 urologists from University Medical Center Mainz (Germany) were asked to plot the location of a cancer suspicious lesion (PI-RADS ≥ 4) on a total of 30 mpMRI on a prostate sector diagram. The following 3 groups (as matched triplets) were divided into: mpMRI only, mpMRI with radiological report and mpMRI with 3D printed model (scaled 1:1). Statistical analysis was performed using one-way and two-way ANOVA (with bonferroni post-test).ResultsOverall, localization of the suspicious lesion was superior with the radiological report (median of max. 10 [IQR]: MRI 2 [IQR 1;5], MRI + report: 8 [6.3;9], MRI + 3D model 3 [1.3;5.8]; p < 0.001). Residents with <1 year of experience had a significantly higher detection rate using a 3D printed model [5 (5;5.8)] compared to mpMRI alone [1.5 (1;3.5)] (p < 0.05). Regarding the estimation of index lesion extension, the 3D model showed a significant benefit (mean percentage difference [95% CI]: MRI alone 234% [17.1;451.5], MRI + report 114% [78.5;149.6], MRI + 3D model 17% [−7.4;41.3] (p < 0.01).ConclusionUrologists still need the written radiological report for a sufficient understanding of tumor localization. The effectiveness of the 3D printed model regarding tumor localization is particularly evident in young residents (<1 year) and leads to a better overall assessment of the tumor extension.https://www.frontiersin.org/articles/10.3389/fsurg.2023.1264164/fullprostateprostate carcinomaprostate biopsyMRI of the prostatePI-RADS3D printed prostate model |
| spellingShingle | Maximilian Haack Katja Reisen Ahmed Ghazy Kristina Stroh Lisa Frey Peter Sparwasser Gregor Duwe Rene Mager Axel Haferkamp Hendrik Borgmann Hendrik Borgmann Understanding tumor localization in multiparametric MRI of the prostate—effectiveness of 3D printed models Frontiers in Surgery prostate prostate carcinoma prostate biopsy MRI of the prostate PI-RADS 3D printed prostate model |
| title | Understanding tumor localization in multiparametric MRI of the prostate—effectiveness of 3D printed models |
| title_full | Understanding tumor localization in multiparametric MRI of the prostate—effectiveness of 3D printed models |
| title_fullStr | Understanding tumor localization in multiparametric MRI of the prostate—effectiveness of 3D printed models |
| title_full_unstemmed | Understanding tumor localization in multiparametric MRI of the prostate—effectiveness of 3D printed models |
| title_short | Understanding tumor localization in multiparametric MRI of the prostate—effectiveness of 3D printed models |
| title_sort | understanding tumor localization in multiparametric mri of the prostate effectiveness of 3d printed models |
| topic | prostate prostate carcinoma prostate biopsy MRI of the prostate PI-RADS 3D printed prostate model |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2023.1264164/full |
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