A cross-sectional and longitudinal study evaluating brain volumes, RNFL, and cognitive functions in MS patients and healthy controls

A cross-sectional and longitudinal study evaluating brain volumes, RNFL, and cognitive functions in MS patients and healthy controls

Abstract Background The principal biomarker of neurodegeneration in multiple sclerosis (MS) is believed to be brain volume, which is associated with cognitive functions and retinal nerve fibre layer (RNFL). A cross-sectional and longitudinal assessment of the relationship between RNFL, cognitive fun...

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Bibliographic Details
Main Authors: Jessica Frau, Giuseppe Fenu, Alessio Signori, Giancarlo Coghe, Lorena Lorefice, Maria Antonietta Barracciu, Vincenzo Sechi, Federico Cabras, Mauro Badas, Maria Giovanna Marrosu, Eleonora Cocco
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Neurology
Subjects:
Multiple sclerosis
Brain volume
Retinal nerve Fiber layer thickness
Cognitive impairments
BICAMS
Online Access:http://link.springer.com/article/10.1186/s12883-018-1065-9

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