Aspartate β-Hydroxylase (ASPH) Expression in Acute Myeloid Leukemia: A Potential Novel Therapeutic Target

Aspartate β-Hydroxylase (ASPH) Expression in Acute Myeloid Leukemia: A Potential Novel Therapeutic Target

BackgroundAspartate β-hydroxylase (ASPH) is an embryonic transmembrane protein aberrantly upregulated in cancer cells, associated with malignant transformation and, in some reports, with poor clinical prognosis.ObjectiveTo report the expression patterns of ASPH in acute myeloid leukemia (AML).Method...

Full description

Bibliographic Details
Main Authors:	Noa G. Holtzman, Michael S. Lebowitz, Rima Koka, Maria R. Baer, Kanam Malhotra, Amir Shahlaee, Hossein A. Ghanbari, Søren M. Bentzen, Ashkan Emadi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-12-01
Series:	Frontiers in Oncology
Subjects:	leukemia myeloid myeloblasts ASPH leukemia-associated antigen
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2021.783744/full

Similar Items

ASPH Regulates Osteogenic Differentiation and Cellular Senescence of BMSCs
by: Hui Peng, et al.
Published: (2020-09-01)

Aspartate β-Hydroxylase Serves as a Prognostic Biomarker for Neoadjuvant Chemotherapy in Gastric Cancer
by: Xuejun Gan, et al.
Published: (2023-03-01)

Aspartate-β-Hydroxylase: A Promising Target to Limit the Local Invasiveness of Colorectal Cancer
by: Roberto Benelli, et al.
Published: (2020-04-01)

Diagnosis of large granular lymphocytic leukemia in a patient previously treated for acute myeloblastic leukemia
by: Sinem Civriz Bozdag, et al.
Published: (2013-12-01)

Certain Killer Immunoglobulin-Like Receptor (KIR)/KIR HLA Class I Ligand Genotypes Influence Natural Killer Antitumor Activity in Myelogenous Leukemia but Not in Acute Lymphoblastic Leukemia: A Case Control Leukemia Association Study
by: Viktoria Varbanova, et al.
Published: (2019-11-01)

Features of Childhood Acute Myeloid Leukemia in Iran: a Report from Double Center Study
by: Azim Mehrvar, et al.
Published: (2015-12-01)

Atypical presentation of herpes zoster in a case with acute myeloblastic leukemia
by: Fesih Aktar, et al.
Published: (2013-01-01)

Dual targeting of glutamine and serine metabolism in acute myeloid leukemia
by: Kanwal M. Hameed, et al.
Published: (2024-04-01)

Frontline Blinatumomab in Older Adults with Philadelphia Chromosome-Negative B-Cell Acute Lymphoblastic Leukemia
by: Sandrine Niyongere, et al.
Published: (2020-06-01)

Profiling 25 Bone Marrow microRNAs in Acute Leukemias and Secondary Nonleukemic Hematopoietic Conditions
by: Igor B. Kovynev, et al.
Published: (2020-12-01)

Etiology of Acute Leukemia: A Review
by: Cameron K. Tebbi
Published: (2021-05-01)

Bacteremia Due to Corynebacterium jeikeium in a Patient with Acute Myeloblastic Leukemia: Case Report
by: Çiğdem KUZUCU, et al.
Published: (2003-06-01)

Proptosis, a rare presentation of acute myeloid leukemia − AML M6 in a child
by: Ragalikhith Kesamneni, et al.
Published: (2016-01-01)

Transient thrombocytosis with megathrombocytes in a case of acute myeloblastic leukemia
by: Kotru Mrinalini, et al.
Published: (2009-01-01)

1-C Metabolism—Serine, Glycine, Folates—In Acute Myeloid Leukemia
by: Kanwal Mahmood, et al.
Published: (2021-02-01)

ASPH-notch Axis guided Exosomal delivery of Prometastatic Secretome renders breast Cancer multi-organ metastasis
by: Qiushi Lin, et al.
Published: (2019-11-01)

Persistently high incidence rates of childhood acute leukemias from 2010 to 2017 in Mexico City: A population study from the MIGICCL
by: Janet Flores-Lujano, et al.
Published: (2022-09-01)

Study of SFRP1 and SFRP2 Genes Methylation Status in Patients with De Novo Acute Myeloblastic Leukemia
by: Ali Ghasemi, et al.
Published: (2014-07-01)

Intestinal mucus accumulation in a child with acutemyeloblastic leukemia
by: Namık Özbek, et al.
Published: (2009-12-01)

A Case of Bacteremia Caused by Herbaspirillum huttiense in an Immunosuppressive Patient and Literature Review
by: Nurullah UZUNER, et al.
Published: (2021-03-01)

EXPRESSION OF EXTRAPOLATIVE FACTORS OF MEDICAL IMPORTANCE AND THEIR POTENTIAL ROLE IN THE DEVELOPMENT OF LEUKEMIA
by: Arif Malik, et al.
Published: (2018-04-01)

Therapeutic Outcomes of Pediatric Acute Myeloblastic Leukemia Patients at a Tertiary Hospital in Bandung, Indonesia
by: Filbert Lois Marcus, et al.
Published: (2022-03-01)

THE CONDITION OF THE HARD TISSUES OF THE TEETH IN CHILDREN WITH ACUTE FORMS OF LEUKEMIA
by: О.V. Lehenchuk, et al.
Published: (2021-03-01)

Outcomes of Newly Diagnosed Acute Myeloid Leukemia Patients Treated With Hypomethylating Agents With or Without Venetoclax: A Propensity Score-Adjusted Cohort Study
by: Moaath K. Mustafa Ali, et al.
Published: (2022-03-01)

CircASPH Promotes Hepatocellular Carcinoma Progression Through Methylation and Expression of HAO2
by: Han Zhuo, et al.
Published: (2022-06-01)

Erwinia asparaginase (crisantaspase) increases plasma levels of serine and glycine
by: Dominique Bollino, et al.
Published: (2022-12-01)

Iron Overload in Children with Acute Lymphoblastic and Acute Myeloblastic Leukemia—Experience of One Center
by: Malgorzata Sawicka-Zukowska, et al.
Published: (2024-01-01)

Minimally-Myelosuppressive Asparaginase-Containing Induction Regimen for Treatment of a Jehovah’s Witness with mutant IDH1/NPM1/NRAS Acute Myeloid Leukemia
by: Ashkan Emadi, et al.
Published: (2016-03-01)

A Comparison of Allogeneic and Autologous Hematopoietic Stem Cell Transplantation for Acute Myeloblastic Leukemia
by: Ardeshir Ghavamzadeh, et al.
Published: (2009-03-01)

A Comparison of Allogeneic and Autologous Hematopoietic Stem Cell Transplantation for Acute Myeloblastic Leukemia
by: Farnaz Khatami, et al.
Published: (2009-01-01)

Pseudo Chediak-Higashi Anomaly
by: Zekai Avcı, et al.
Published: (2013-06-01)

Azacitidine as salvage therapy for acute myeloid leukemia in a severely ill patient
by: Harry Ross Powers, et al.
Published: (2014-09-01)

H1N1 associated encephalitis in a child with acute myeloblastic leukemia and bacteremia due to Klebsiella pneumonia
by: Lale Olcay, et al.
Published: (2012-03-01)

A Rare Case of Acute Myeloblastc Leukemia With Blast Count Less Than 20% in Bone Marrow
by: Pardis Nematollahi, et al.
Published: (2019-07-01)

Clinical Manifestations and Hematological Profiles of Pediatric Acute Myeloblastic Leukemia Patients: 3 Years Observational Study in A West Java Tertiary Hospital, Indonesia
by: Agustinus Wiraatmadja, et al.
Published: (2019-09-01)

Xeroderma pigmentosum and acute myeloid leukemia: a case report
by: H. Bencharef, et al.
Published: (2021-08-01)

Mucormycosis in a patient with acute myeloblastic leukemia following liver transplantation for Wilson’s disease
by: Aleksandra Anna Łanocha, et al.
Published: (2019-12-01)

Therapy-related B-lymphoblastic leukemia after multiple myeloma
by: Michael E. Kallen, et al.
Published: (2022-01-01)

Risk factors of CMV replication after allogeneic hematopoietic stem cell transplantation in children and adolescents
by: S. N. Shiriaev, et al.
Published: (2014-09-01)

Risk factors of CMV replication after allogeneic hematopoietic stem cell transplantation in children and adolescents
by: S. N. Shiriaev, et al.
Published: (2014-09-01)