Residue behavior and dietary risk assessment of six pesticides in pak choi using QuEChERS method coupled with UPLC-MS/MS
A reliable and simple modified QuEChERS method with UPLC-MS/MS was developed for the simultaneous determination of six pesticides (dimethomorph, imidaclothiz, lufenuron, methoxyfenozide, pyridaben, spinetoram) and their metabolites in pak choi. Method validation indicated good linearity (R2 ≥ 0.99),...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-04-01
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| Series: | Ecotoxicology and Environmental Safety |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651321001330 |
| _version_ | 1818740131567239168 |
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| author | Hongxia Tang Lin Ma Jiaqing Huang Yubo Li Zehui Liu Dianying Meng Guangyue Wen Maofeng Dong Weimin Wang Li Zhao |
| author_facet | Hongxia Tang Lin Ma Jiaqing Huang Yubo Li Zehui Liu Dianying Meng Guangyue Wen Maofeng Dong Weimin Wang Li Zhao |
| author_sort | Hongxia Tang |
| collection | DOAJ |
| description | A reliable and simple modified QuEChERS method with UPLC-MS/MS was developed for the simultaneous determination of six pesticides (dimethomorph, imidaclothiz, lufenuron, methoxyfenozide, pyridaben, spinetoram) and their metabolites in pak choi. Method validation indicated good linearity (R2 ≥ 0.99), accuracy (recoveries of 75%−112%), sensitivity (limits of quantification, 0.002–0.01 mg kg−1), and precision (relative standard deviations ≤ 21%), and matrix effects were −36–28%. The half-lives of the six pesticides in pak choi were 2.2–12 d under open field and greenhouse conditions. Considering the short growth cycle of pak choi, the terminal residue levels (0.046–7.8 mg kg−1) and the relevant maximum residue limits (MRLs) of some countries, 5 d was recommended as the pre-harvest interval for the six pesticides on pak choi. Dietary risk assessment revealed that the risk quotients were 3.1%−58% for different gender and age groups in China, indicating none unacceptable public health risk for general population. The results showed that all the six pesticides degraded faster and the terminal residues were much lower under open field conditions than those under greenhouse conditions, which was mainly due to the influence of rainfall, sunlight and other environmental factors. This work was thus significant in assessing the dissipation fate and food safety risks of the six pesticides on pak choi and facilitated the establishment of maximum residue limits. |
| first_indexed | 2024-12-18T01:35:51Z |
| format | Article |
| id | doaj.art-f8711968832549fbb9e31ef966c48776 |
| institution | Directory Open Access Journal |
| issn | 0147-6513 |
| language | English |
| last_indexed | 2024-12-18T01:35:51Z |
| publishDate | 2021-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Ecotoxicology and Environmental Safety |
| spelling | doaj.art-f8711968832549fbb9e31ef966c487762022-12-21T21:25:28ZengElsevierEcotoxicology and Environmental Safety0147-65132021-04-01213112022Residue behavior and dietary risk assessment of six pesticides in pak choi using QuEChERS method coupled with UPLC-MS/MSHongxia Tang0Lin Ma1Jiaqing Huang2Yubo Li3Zehui Liu4Dianying Meng5Guangyue Wen6Maofeng Dong7Weimin Wang8Li Zhao9Pesticide Safety Evaluation Research Center, Institute for Agro-food Standards and Testing Technology, Shanghai Academy of Agricultural Sciences, Shanghai 201106, PR ChinaShanghai Agriculture Technical Extension Service Center, Shanghai 201103, PR ChinaPesticide Safety Evaluation Research Center, Institute for Agro-food Standards and Testing Technology, Shanghai Academy of Agricultural Sciences, Shanghai 201106, PR ChinaPesticide Safety Evaluation Research Center, Institute for Agro-food Standards and Testing Technology, Shanghai Academy of Agricultural Sciences, Shanghai 201106, PR ChinaPesticide Safety Evaluation Research Center, Institute for Agro-food Standards and Testing Technology, Shanghai Academy of Agricultural Sciences, Shanghai 201106, PR ChinaPesticide Safety Evaluation Research Center, Institute for Agro-food Standards and Testing Technology, Shanghai Academy of Agricultural Sciences, Shanghai 201106, PR ChinaPesticide Safety Evaluation Research Center, Institute for Agro-food Standards and Testing Technology, Shanghai Academy of Agricultural Sciences, Shanghai 201106, PR ChinaPesticide Safety Evaluation Research Center, Institute for Agro-food Standards and Testing Technology, Shanghai Academy of Agricultural Sciences, Shanghai 201106, PR China; Corresponding authors.Pesticide Safety Evaluation Research Center, Institute for Agro-food Standards and Testing Technology, Shanghai Academy of Agricultural Sciences, Shanghai 201106, PR China; Corresponding authors.Shanghai Agriculture Technical Extension Service Center, Shanghai 201103, PR ChinaA reliable and simple modified QuEChERS method with UPLC-MS/MS was developed for the simultaneous determination of six pesticides (dimethomorph, imidaclothiz, lufenuron, methoxyfenozide, pyridaben, spinetoram) and their metabolites in pak choi. Method validation indicated good linearity (R2 ≥ 0.99), accuracy (recoveries of 75%−112%), sensitivity (limits of quantification, 0.002–0.01 mg kg−1), and precision (relative standard deviations ≤ 21%), and matrix effects were −36–28%. The half-lives of the six pesticides in pak choi were 2.2–12 d under open field and greenhouse conditions. Considering the short growth cycle of pak choi, the terminal residue levels (0.046–7.8 mg kg−1) and the relevant maximum residue limits (MRLs) of some countries, 5 d was recommended as the pre-harvest interval for the six pesticides on pak choi. Dietary risk assessment revealed that the risk quotients were 3.1%−58% for different gender and age groups in China, indicating none unacceptable public health risk for general population. The results showed that all the six pesticides degraded faster and the terminal residues were much lower under open field conditions than those under greenhouse conditions, which was mainly due to the influence of rainfall, sunlight and other environmental factors. This work was thus significant in assessing the dissipation fate and food safety risks of the six pesticides on pak choi and facilitated the establishment of maximum residue limits.http://www.sciencedirect.com/science/article/pii/S0147651321001330Pak choiPesticidesSafety evaluationResidues levelDissipation |
| spellingShingle | Hongxia Tang Lin Ma Jiaqing Huang Yubo Li Zehui Liu Dianying Meng Guangyue Wen Maofeng Dong Weimin Wang Li Zhao Residue behavior and dietary risk assessment of six pesticides in pak choi using QuEChERS method coupled with UPLC-MS/MS Ecotoxicology and Environmental Safety Pak choi Pesticides Safety evaluation Residues level Dissipation |
| title | Residue behavior and dietary risk assessment of six pesticides in pak choi using QuEChERS method coupled with UPLC-MS/MS |
| title_full | Residue behavior and dietary risk assessment of six pesticides in pak choi using QuEChERS method coupled with UPLC-MS/MS |
| title_fullStr | Residue behavior and dietary risk assessment of six pesticides in pak choi using QuEChERS method coupled with UPLC-MS/MS |
| title_full_unstemmed | Residue behavior and dietary risk assessment of six pesticides in pak choi using QuEChERS method coupled with UPLC-MS/MS |
| title_short | Residue behavior and dietary risk assessment of six pesticides in pak choi using QuEChERS method coupled with UPLC-MS/MS |
| title_sort | residue behavior and dietary risk assessment of six pesticides in pak choi using quechers method coupled with uplc ms ms |
| topic | Pak choi Pesticides Safety evaluation Residues level Dissipation |
| url | http://www.sciencedirect.com/science/article/pii/S0147651321001330 |
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