Simulated Microgravity Altered the Metabolism of Loureirin B and the Expression of Major Cytochrome P450 in Liver of Rats

Loureirin B (LB) is the marker compound of dragon blood (DB), which exhibits great potentials in protecting astronauts’ health against radiation and simulated microgravity (SM). Pharmacokinetics of LB is reported to be significantly altered by SM. Here, we investigated key metabolic features of LB i...

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Détails bibliographiques
Auteurs principaux: Bo Chen, Jingjing Guo, Shibo Wang, Liting Kang, Yulin Deng, Yujuan Li
Format: Article
Langue:English
Publié: Frontiers Media S.A. 2018-10-01
Collection:Frontiers in Pharmacology
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Accès en ligne:https://www.frontiersin.org/article/10.3389/fphar.2018.01130/full