Simulated Microgravity Altered the Metabolism of Loureirin B and the Expression of Major Cytochrome P450 in Liver of Rats

Simulated Microgravity Altered the Metabolism of Loureirin B and the Expression of Major Cytochrome P450 in Liver of Rats

Loureirin B (LB) is the marker compound of dragon blood (DB), which exhibits great potentials in protecting astronauts’ health against radiation and simulated microgravity (SM). Pharmacokinetics of LB is reported to be significantly altered by SM. Here, we investigated key metabolic features of LB i...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Bo Chen, Jingjing Guo, Shibo Wang, Liting Kang, Yulin Deng, Yujuan Li
Format: Artykuł
Język:English
Wydane: Frontiers Media S.A. 2018-10-01
Seria:Frontiers in Pharmacology
Hasła przedmiotowe:
simulated microgravity
dragon blood
loureirin B
liver microsome
hepatic cytochrome P450
drug metabolism
Dostęp online:https://www.frontiersin.org/article/10.3389/fphar.2018.01130/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01130/full

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