Full-Thickness Resection Device for Complex Colorectal Lesions in High-Risk Patients as a Last-Resort Endoscopic Treatment: Initial Clinical Experience and Review of the Current Literature
The full-thickness resection device (FTRD) is a novel endoscopic device approved for the resection of colorectal lesions. This case-series describes the device and its use in high-risk patients with colorectal lesions and provides an overview of the potential indications in recently published data....
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Format: | Article |
Language: | English |
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Korean Society of Gastrointestinal Endoscopy
2018-01-01
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Series: | Clinical Endoscopy |
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Online Access: | http://www.e-ce.org/upload/pdf/ce-2017-093.pdf |
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author | Edris Wedi Beatrice Orlandini Mark Gromski Carlo Felix Maria Jung Irina Tchoumak Stephanie Boucher Volker Ellenrieder Jürgen Hochberger |
author_facet | Edris Wedi Beatrice Orlandini Mark Gromski Carlo Felix Maria Jung Irina Tchoumak Stephanie Boucher Volker Ellenrieder Jürgen Hochberger |
author_sort | Edris Wedi |
collection | DOAJ |
description | The full-thickness resection device (FTRD) is a novel endoscopic device approved for the resection of colorectal lesions. This case-series describes the device and its use in high-risk patients with colorectal lesions and provides an overview of the potential indications in recently published data. Between December 2014 and September 2015, 3 patients underwent endoscopic full thickness resection using the FTRD for colorectal lesions: 1 case for a T1 adenocarcinoma in the region of a surgical anastomosis after recto-sigmoidectomy, 1 case for a non-lifting colonic adenoma with low-grade dysplasia in an 89-year old patient and 1 for a recurrent adenoma with high-grade dysplasia in a young patient with ulcerative rectocolitis who was under immunosuppression after renal transplantation. Both technical and clinical success rates were achieved in all cases. The size of removed lesions ranged from 9 to 30 mm. Overall, the most frequent indication in the literature has been for lifting or non-lifting adenoma, submucosal tumors, neuroendocrin tumors, incomplete endoscopic resection (R1) or T1 carcinoma. Colorectal FTRD is a feasible technique for the treatment of colorectal lesions and represents a minimally invasive alternative for either surgical or conventional endoscopic resection strategies. |
first_indexed | 2024-03-09T07:49:16Z |
format | Article |
id | doaj.art-f87645170c3245c2aa9192751b6d34c8 |
institution | Directory Open Access Journal |
issn | 2234-2400 2234-2443 |
language | English |
last_indexed | 2024-03-09T07:49:16Z |
publishDate | 2018-01-01 |
publisher | Korean Society of Gastrointestinal Endoscopy |
record_format | Article |
series | Clinical Endoscopy |
spelling | doaj.art-f87645170c3245c2aa9192751b6d34c82023-12-03T02:14:29ZengKorean Society of Gastrointestinal EndoscopyClinical Endoscopy2234-24002234-24432018-01-0151110310810.5946/ce.2017.0937073Full-Thickness Resection Device for Complex Colorectal Lesions in High-Risk Patients as a Last-Resort Endoscopic Treatment: Initial Clinical Experience and Review of the Current LiteratureEdris Wedi0Beatrice Orlandini1Mark Gromski2Carlo Felix Maria Jung3Irina Tchoumak4Stephanie Boucher5Volker Ellenrieder6Jürgen Hochberger7 Department of Gastroenterology and Gastrointestinal Oncology, University Medical Center Göttingen, Göttingen, Germany Department of Gastroenterology, Careggi University Hospital, Florence, Italy Division of Gastroenterology, Indiana University School of Medicine, Indianapolis, IN, USA Department of Gastroenterology and Gastrointestinal Oncology, University Medical Center Göttingen, Göttingen, Germany Department of Gastroenterology and Gastrointestinal Oncology, University Medical Center Göttingen, Göttingen, Germany Department of Pathology, Nouvel Hôpital Civil, Strasbourg University Hospitals, Strasbourg, France Department of Gastroenterology and Gastrointestinal Oncology, University Medical Center Göttingen, Göttingen, Germany 5Department of Internal Medicine, Vivantes Klinikum im Friedrichshain, University Teaching Hospital of Humboldt University Berlin (Charité), Berlin, GermanyThe full-thickness resection device (FTRD) is a novel endoscopic device approved for the resection of colorectal lesions. This case-series describes the device and its use in high-risk patients with colorectal lesions and provides an overview of the potential indications in recently published data. Between December 2014 and September 2015, 3 patients underwent endoscopic full thickness resection using the FTRD for colorectal lesions: 1 case for a T1 adenocarcinoma in the region of a surgical anastomosis after recto-sigmoidectomy, 1 case for a non-lifting colonic adenoma with low-grade dysplasia in an 89-year old patient and 1 for a recurrent adenoma with high-grade dysplasia in a young patient with ulcerative rectocolitis who was under immunosuppression after renal transplantation. Both technical and clinical success rates were achieved in all cases. The size of removed lesions ranged from 9 to 30 mm. Overall, the most frequent indication in the literature has been for lifting or non-lifting adenoma, submucosal tumors, neuroendocrin tumors, incomplete endoscopic resection (R1) or T1 carcinoma. Colorectal FTRD is a feasible technique for the treatment of colorectal lesions and represents a minimally invasive alternative for either surgical or conventional endoscopic resection strategies.http://www.e-ce.org/upload/pdf/ce-2017-093.pdfColonoscopyColorectal neoplasmsFull-thickness resection deviceOver-the-scope-clip |
spellingShingle | Edris Wedi Beatrice Orlandini Mark Gromski Carlo Felix Maria Jung Irina Tchoumak Stephanie Boucher Volker Ellenrieder Jürgen Hochberger Full-Thickness Resection Device for Complex Colorectal Lesions in High-Risk Patients as a Last-Resort Endoscopic Treatment: Initial Clinical Experience and Review of the Current Literature Clinical Endoscopy Colonoscopy Colorectal neoplasms Full-thickness resection device Over-the-scope-clip |
title | Full-Thickness Resection Device for Complex Colorectal Lesions in High-Risk Patients as a Last-Resort Endoscopic Treatment: Initial Clinical Experience and Review of the Current Literature |
title_full | Full-Thickness Resection Device for Complex Colorectal Lesions in High-Risk Patients as a Last-Resort Endoscopic Treatment: Initial Clinical Experience and Review of the Current Literature |
title_fullStr | Full-Thickness Resection Device for Complex Colorectal Lesions in High-Risk Patients as a Last-Resort Endoscopic Treatment: Initial Clinical Experience and Review of the Current Literature |
title_full_unstemmed | Full-Thickness Resection Device for Complex Colorectal Lesions in High-Risk Patients as a Last-Resort Endoscopic Treatment: Initial Clinical Experience and Review of the Current Literature |
title_short | Full-Thickness Resection Device for Complex Colorectal Lesions in High-Risk Patients as a Last-Resort Endoscopic Treatment: Initial Clinical Experience and Review of the Current Literature |
title_sort | full thickness resection device for complex colorectal lesions in high risk patients as a last resort endoscopic treatment initial clinical experience and review of the current literature |
topic | Colonoscopy Colorectal neoplasms Full-thickness resection device Over-the-scope-clip |
url | http://www.e-ce.org/upload/pdf/ce-2017-093.pdf |
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