Simultaneous selection of multiple important single nucleotide polymorphisms in familial genome wide association studies data

Abstract We propose a resampling-based fast variable selection technique for detecting relevant single nucleotide polymorphisms (SNP) in a multi-marker mixed effect model. Due to computational complexity, current practice primarily involves testing the effect of one SNP at a time, commonly termed as...

Full description

Bibliographic Details
Main Authors: Subhabrata Majumdar, Saonli Basu, Matt McGue, Snigdhansu Chatterjee
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-35379-y