Simultaneous selection of multiple important single nucleotide polymorphisms in familial genome wide association studies data
Abstract We propose a resampling-based fast variable selection technique for detecting relevant single nucleotide polymorphisms (SNP) in a multi-marker mixed effect model. Due to computational complexity, current practice primarily involves testing the effect of one SNP at a time, commonly termed as...
Main Authors: | Subhabrata Majumdar, Saonli Basu, Matt McGue, Snigdhansu Chatterjee |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-05-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-35379-y |
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