Enzyme kinetics of dUTPase from the planarian Dugesia ryukyuensis

Enzyme kinetics of dUTPase from the planarian Dugesia ryukyuensis

Abstract Objective Planarians including Dugesia ryukyuensis (Dr) have strong regenerative abilities that require enhanced DNA replication. Knockdown of the DUT gene in Dr, which encodes deoxyuridine 5′-triphosphate pyrophosphatase (dUTPase), promotes DNA fragmentation, inhibits regeneration, and eve...

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Bibliographic Details
Main Authors: Md. Shahanoor Alam, Hideaki Moriyama, Midori Matsumoto
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Research Notes
Subjects:
dUTPase
Planarian
Regeneration
Online Access:http://link.springer.com/article/10.1186/s13104-019-4191-6

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