Expression of the RANK/RANKL/OPG system in the human intervertebral disc: implication for the pathogenesis of intervertebral disc degeneration

Expression of the RANK/RANKL/OPG system in the human intervertebral disc: implication for the pathogenesis of intervertebral disc degeneration

Abstract Background The expression of the receptor activator of nuclear factor kappa B (RANK) /RANK ligand (RANKL) /osteoprotegerin (OPG) system and its association with the progression of intervertebral disc (IVD) degeneration has recently been reported in a human IVD. However, the effect of the RA...

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Bibliographic Details
Main Authors: Tomohiko Sano, Koji Akeda, Junichi Yamada, Norihiko Takegami, Takao Sudo, Akihiro Sudo
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Musculoskeletal Disorders
Subjects:
Receptor activator of nuclear factor kappa B
Receptor activator of nuclear factor kappa B ligand
Osteoprotegerin
Intervertebral disc
Degeneration
Anti-receptor activator of nuclear factor kappa B ligand antibody
Online Access:http://link.springer.com/article/10.1186/s12891-019-2609-x

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