Hgc1 Independence of Biofilm Hyphae in Candida albicans

Hgc1 Independence of Biofilm Hyphae in Candida albicans

ABSTRACT Biofilm and hypha formation are central to virulence of the fungal pathogen Candida albicans. The G1 cyclin gene HGC1 is required for hypha formation under diverse in vitro and in vivo growth conditions. Hgc1 is required for disseminated infection and is a linchpin in the argument that hyph...

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Bibliographic Details
Main Authors: Anupam Sharma, Norma V. Solis, Manning Y. Huang, Frederick Lanni, Scott G. Filler, Aaron P. Mitchell
Format: Article
Language:English
Published: American Society for Microbiology 2023-04-01
Series:mBio
Subjects:
biofilm
Candida
hyphae
regulation
virulence
Online Access:https://journals.asm.org/doi/10.1128/mbio.03498-22

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