Bacterial Outer Membrane Vesicles as a Platform for the Development of a Broadly Protective Human Papillomavirus Vaccine Based on the Minor Capsid Protein L2

Bacterial Outer Membrane Vesicles as a Platform for the Development of a Broadly Protective Human Papillomavirus Vaccine Based on the Minor Capsid Protein L2

Human papillomaviruses (HPVs) are a large family of viruses with a capsid composed of the L1 and L2 proteins, which bind to receptors of the basal epithelial cells and promote virus entry. The majority of sexually active people become exposed to HPV and the virus is the most common cause of cervical...

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Bibliographic Details
Main Authors: Silvia Tamburini, Yueru Zhang, Assunta Gagliardi, Gabriele Di Lascio, Elena Caproni, Mattia Benedet, Michele Tomasi, Riccardo Corbellari, Ilaria Zanella, Lorenzo Croia, Guido Grandi, Martin Müller, Alberto Grandi
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Vaccines
Subjects:
outer membrane vesicle (OMV)
proteome minimized <i>E. coli</i>
human papillomavirus (HPV)
minor capsid protein L2
OMV engineering
HPV OMV based vaccine
Online Access:https://www.mdpi.com/2076-393X/11/10/1582

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