C-reactive protein as an inflammatory marker in monitoring therapy effectiveness of acute odontogenic infections
Introduction. Clinical presentation of acute odontogenic infections may vary, while adequate evaluation of its severity is of great importance for determination of appropriate and effective therapy. Objective. The aim of the present study was to monitor changes of C-reactive protein (CRP) levels,...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Serbian Medical Society
2011-01-01
|
| Series: | Srpski Arhiv za Celokupno Lekarstvo |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0370-8179/2011/0370-81791108446D.pdf |
| _version_ | 1818602186739810304 |
|---|---|
| author | Dražić Radojica Jurišić Milan Marković Aleksa Čolić Snježana Gačić Bojan Stojčev-Stajčić Ljiljana |
| author_facet | Dražić Radojica Jurišić Milan Marković Aleksa Čolić Snježana Gačić Bojan Stojčev-Stajčić Ljiljana |
| author_sort | Dražić Radojica |
| collection | DOAJ |
| description | Introduction. Clinical presentation of acute odontogenic infections may vary, while adequate evaluation of its severity is of great importance for determination of appropriate and effective therapy. Objective. The aim of the present study was to monitor changes of C-reactive protein (CRP) levels, to correlate its values with symptoms of different acute odontogenic infections (AOI), and to monitor the effectiveness of the applied therapy. Methods. Fifty-four patients with AOI were included in the study. Eighteen patients with good drainage and normal body temperature were treated only by surgical incision without using antibiotics. Twenty-two patients with poor drainage after incision and normal body temperature were treated by surgical incision and antibiotics. Fourteen patients with elevated body temperature were treated by incision and antibiotics, irrespective of the quality of the drainage. CRP levels were measured on admission, on the 3rd and 7th day after therapy initiation. Results. On admission CRP levels were higher in AOI with elevated body temperature compared to poorly and well-drained AOI. There were no differences in CRP levels between well and poorly drained AOI on admission. On the 3rd day, a decline in the CRP levels was evident in all three groups of patients, and there was no difference among the groups. On the 7th day, the CRP levels normalized in all groups. Conclusion. CRP levels correlate well with the severity and resolution of AOI and could be used as a reliable parameter in monitoring the effectiveness of AOI therapy. |
| first_indexed | 2024-12-16T13:03:17Z |
| format | Article |
| id | doaj.art-f887d2ae885e40ebac79aab4d03b62f5 |
| institution | Directory Open Access Journal |
| issn | 0370-8179 |
| language | English |
| last_indexed | 2024-12-16T13:03:17Z |
| publishDate | 2011-01-01 |
| publisher | Serbian Medical Society |
| record_format | Article |
| series | Srpski Arhiv za Celokupno Lekarstvo |
| spelling | doaj.art-f887d2ae885e40ebac79aab4d03b62f52022-12-21T22:30:47ZengSerbian Medical SocietySrpski Arhiv za Celokupno Lekarstvo0370-81792011-01-011397-844645110.2298/SARH1108446DC-reactive protein as an inflammatory marker in monitoring therapy effectiveness of acute odontogenic infectionsDražić RadojicaJurišić MilanMarković AleksaČolić SnježanaGačić BojanStojčev-Stajčić LjiljanaIntroduction. Clinical presentation of acute odontogenic infections may vary, while adequate evaluation of its severity is of great importance for determination of appropriate and effective therapy. Objective. The aim of the present study was to monitor changes of C-reactive protein (CRP) levels, to correlate its values with symptoms of different acute odontogenic infections (AOI), and to monitor the effectiveness of the applied therapy. Methods. Fifty-four patients with AOI were included in the study. Eighteen patients with good drainage and normal body temperature were treated only by surgical incision without using antibiotics. Twenty-two patients with poor drainage after incision and normal body temperature were treated by surgical incision and antibiotics. Fourteen patients with elevated body temperature were treated by incision and antibiotics, irrespective of the quality of the drainage. CRP levels were measured on admission, on the 3rd and 7th day after therapy initiation. Results. On admission CRP levels were higher in AOI with elevated body temperature compared to poorly and well-drained AOI. There were no differences in CRP levels between well and poorly drained AOI on admission. On the 3rd day, a decline in the CRP levels was evident in all three groups of patients, and there was no difference among the groups. On the 7th day, the CRP levels normalized in all groups. Conclusion. CRP levels correlate well with the severity and resolution of AOI and could be used as a reliable parameter in monitoring the effectiveness of AOI therapy.http://www.doiserbia.nb.rs/img/doi/0370-8179/2011/0370-81791108446D.pdfodontogenic infectionsC-reactive proteinincisiondrainageantibiotic therapy |
| spellingShingle | Dražić Radojica Jurišić Milan Marković Aleksa Čolić Snježana Gačić Bojan Stojčev-Stajčić Ljiljana C-reactive protein as an inflammatory marker in monitoring therapy effectiveness of acute odontogenic infections Srpski Arhiv za Celokupno Lekarstvo odontogenic infections C-reactive protein incision drainage antibiotic therapy |
| title | C-reactive protein as an inflammatory marker in monitoring therapy effectiveness of acute odontogenic infections |
| title_full | C-reactive protein as an inflammatory marker in monitoring therapy effectiveness of acute odontogenic infections |
| title_fullStr | C-reactive protein as an inflammatory marker in monitoring therapy effectiveness of acute odontogenic infections |
| title_full_unstemmed | C-reactive protein as an inflammatory marker in monitoring therapy effectiveness of acute odontogenic infections |
| title_short | C-reactive protein as an inflammatory marker in monitoring therapy effectiveness of acute odontogenic infections |
| title_sort | c reactive protein as an inflammatory marker in monitoring therapy effectiveness of acute odontogenic infections |
| topic | odontogenic infections C-reactive protein incision drainage antibiotic therapy |
| url | http://www.doiserbia.nb.rs/img/doi/0370-8179/2011/0370-81791108446D.pdf |
| work_keys_str_mv | AT drazicradojica creactiveproteinasaninflammatorymarkerinmonitoringtherapyeffectivenessofacuteodontogenicinfections AT jurisicmilan creactiveproteinasaninflammatorymarkerinmonitoringtherapyeffectivenessofacuteodontogenicinfections AT markovicaleksa creactiveproteinasaninflammatorymarkerinmonitoringtherapyeffectivenessofacuteodontogenicinfections AT colicsnjezana creactiveproteinasaninflammatorymarkerinmonitoringtherapyeffectivenessofacuteodontogenicinfections AT gacicbojan creactiveproteinasaninflammatorymarkerinmonitoringtherapyeffectivenessofacuteodontogenicinfections AT stojcevstajcicljiljana creactiveproteinasaninflammatorymarkerinmonitoringtherapyeffectivenessofacuteodontogenicinfections |