OCT4 positively regulates Survivin expression to promote cancer cell proliferation and leads to poor prognosis in esophageal squamous cell carcinoma.

OCT4 positively regulates Survivin expression to promote cancer cell proliferation and leads to poor prognosis in esophageal squamous cell carcinoma.

BACKGROUND: OCT4 and Survivin are important factors for cancer cell proliferation, renewal and dedifferentiation, and correlate with resistance to radiotherapy and chemotherapy in most human cancers, but their regulatory mechanisms are not well known. METHODOLOGY/PRINCIPAL FINDINGS: In this study, 5...

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Bibliographic Details
Main Authors: Chunguang Li, Yan Yan, Weidan Ji, Longlong Bao, Haihua Qian, Lei Chen, Mengchao Wu, Hezhong Chen, Zhigang Li, Changqing Su
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3504152?pdf=render

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