Mouse-adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge.

Mouse-adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge.

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The emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a pandemic causing significant damage to public health and the economy. Efforts to understand the mechanisms of Coronavirus Disease 2019 (COVID-19) have been hampered by the lack of robust mouse models. To...

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Bibliographic Details
Main Authors: Antonio Muruato, Michelle N Vu, Bryan A Johnson, Meredith E Davis-Gardner, Abigail Vanderheiden, Kumari Lokugamage, Craig Schindewolf, Patricia A Crocquet-Valdes, Rose M Langsjoen, Jessica A Plante, Kenneth S Plante, Scott C Weaver, Kari Debbink, Andrew L Routh, David Walker, Mehul S Suthar, Pei-Yong Shi, Xuping Xie, Vineet D Menachery
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-11-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001284

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