Cardiovascular Risk in Patients With Takayasu Arteritis Directly Correlates With Diastolic Dysfunction and Inflammatory Cell Infiltration in the Vessel Wall: A Clinical, ex vivo and in vitro Analysis

Cardiovascular Risk in Patients With Takayasu Arteritis Directly Correlates With Diastolic Dysfunction and Inflammatory Cell Infiltration in the Vessel Wall: A Clinical, ex vivo and in vitro Analysis

BackgroundTakayasu Arteritis (TAK) increases vascular stiffness and arterial resistance. Atherosclerosis leads to similar changes. We investigated possible differences in cardiovascular remodeling between these diseases and whether the differences are correlated with immune cell expression.MethodsPa...

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Bibliographic Details
Main Authors: Sebastiano Cicco, Vanessa Desantis, Antonio Vacca, Gerardo Cazzato, Antonio G. Solimando, Anna Cirulli, Silvia Noviello, Cecilia Susca, Marcella Prete, Gabriele Brosolo, Cristiana Catena, Aurelia Lamanuzzi, Ilaria Saltarella, Maria Antonia Frassanito, Antonella Cimmino, Giuseppe Ingravallo, Leonardo Resta, Roberto Ria, Monica Montagnani
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Medicine
Subjects:
Takayasu arteritis (TAK)
echocardiography
immune cell infiltration
vascular stiffness
T helper-like cells
Regulatory T Lymphocytes (Tregs)
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.863150/full

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