Global Genome Mining Reveals the Distribution of Diverse Thioamidated RiPP Biosynthesis Gene Clusters

Global Genome Mining Reveals the Distribution of Diverse Thioamidated RiPP Biosynthesis Gene Clusters

Thioamidated ribosomally synthesized and post-translationally modified peptides (RiPPs) are recently characterized natural products with wide range of potent bioactivities, such as antibiotic, antiproliferative, and cytotoxic activities. These peptides are distinguished by the presence of thioamide...

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Bibliographic Details
Main Authors: Jessie James Limlingan Malit, Chuanhai Wu, Ling-Li Liu, Pei-Yuan Qian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Microbiology
Subjects:
TfuA
RiPPs
genome mining
YcaO
biosynthesis pathway
thioamide
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.635389/full

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