Hedgehog: A Key Signaling in the Development of the Oligodendrocyte Lineage

Hedgehog: A Key Signaling in the Development of the Oligodendrocyte Lineage

The Hedgehog morphogen aroused an enormous interest since it was characterized as an essential signal for ventral patterning of the spinal cord two decades ago. The pathway is notably implicated in the initial appearance of the progenitors of oligodendrocytes (OPCs), the glial cells of the central n...

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Bibliographic Details
Main Authors: Elisabeth Traiffort, Mary Zakaria, Yousra Laouarem, Julien Ferent
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Journal of Developmental Biology
Subjects:
oligodendrocyte
neural tube
forebrain
optic nerve
Smoothened
Patched
Gli
Online Access:http://www.mdpi.com/2221-3759/4/3/28

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