Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes

Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes

Extracellular vesicles (EVs) encompass a variety of vesicles secreted into the extracellular space. EVs have been implicated in promoting tumor metastasis, but the molecular composition of tumor-derived EV sub-types and the mechanisms by which molecules are sorted into EVs remain mostly unknown. We...

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Bibliographic Details
Main Authors: Morayma M Temoche-Diaz, Matthew J Shurtleff, Ryan M Nottingham, Jun Yao, Raj P Fadadu, Alan M Lambowitz, Randy Schekman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-08-01
Series:eLife
Subjects:
extracellular vesicles
miRNA
Lupus La
multivesicular bodies
Online Access:https://elifesciences.org/articles/47544

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