Uterine Fibroid Embolization in a Series of Women Older Than 50 Years: An Observational Study

Objective: Women older than 50 years, and in particular postmenopausal, are not usually considered candidate for uterine artery embolization (UAE). We reviewed the outcome of UAE in a series of women older than 50 years, who presented with different symptoms of uterus enlargement. Population: Women...

Full description

Bibliographic Details
Main Authors: Benedetto Mondelli, Woodruff John Walker, Tanveer Dhanoya, Karen Morton
Format: Article
Language:English
Published: Mary Ann Liebert 2022-02-01
Series:Women's Health Reports
Subjects:
Online Access:https://www.liebertpub.com/doi/full/10.1089/WHR.2021.0057
_version_ 1827373819997716480
author Benedetto Mondelli
Woodruff John Walker
Tanveer Dhanoya
Karen Morton
author_facet Benedetto Mondelli
Woodruff John Walker
Tanveer Dhanoya
Karen Morton
author_sort Benedetto Mondelli
collection DOAJ
description Objective: Women older than 50 years, and in particular postmenopausal, are not usually considered candidate for uterine artery embolization (UAE). We reviewed the outcome of UAE in a series of women older than 50 years, who presented with different symptoms of uterus enlargement. Population: Women referred to the radiologist from gynecologists in the United Kingdom with minimal age over 50 years. Methods: This is a retrospective observational study. The clinical criteria are women older than 50 years with symptoms related to large fibroids affecting their quality of life, who underwent UAE over a 4-year period at Royal Surrey Foundation Trust Hospital and London Clinic between 2012 and 2016. We retrieved the information from the patients' hospital notes and respective images, including magnetic resonance and ultrasound of the pelvis, and from questionnaires and telephone reviews. Main Outcome Measures: We measured the reduction of uterine size, complications, and overall satisfaction of patients. Results: The overall reduction of uterine size 8 weeks following UAE was between 50% and 64% in 12 out of 23 patients. Thirty-five percent of patients (8/23) experienced a reduction of over 65% of overall uterine volume. Only on 2 occasions, the reduction was below 50%. We asked the patients if they would recommend this operation. Twenty out of 23 would recommend it. Improvement of symptoms was measured with a scale between 0 and 5. Twelve out of 23 had total resolution of symptoms?no change in 1 case. One patient underwent a hysterectomy as symptoms persisted. Conclusions: In our series of women older than 50 years, UAE was an effective alternative to surgery, with reduction in fibroid size and improvement of symptoms.
first_indexed 2024-03-08T11:23:05Z
format Article
id doaj.art-f89afd11c3e543188cbbb8c92f1f4fd3
institution Directory Open Access Journal
issn 2688-4844
language English
last_indexed 2024-03-08T11:23:05Z
publishDate 2022-02-01
publisher Mary Ann Liebert
record_format Article
series Women's Health Reports
spelling doaj.art-f89afd11c3e543188cbbb8c92f1f4fd32024-01-26T05:57:08ZengMary Ann LiebertWomen's Health Reports2688-48442022-02-013123824210.1089/WHR.2021.0057Uterine Fibroid Embolization in a Series of Women Older Than 50 Years: An Observational StudyBenedetto MondelliWoodruff John WalkerTanveer DhanoyaKaren MortonObjective: Women older than 50 years, and in particular postmenopausal, are not usually considered candidate for uterine artery embolization (UAE). We reviewed the outcome of UAE in a series of women older than 50 years, who presented with different symptoms of uterus enlargement. Population: Women referred to the radiologist from gynecologists in the United Kingdom with minimal age over 50 years. Methods: This is a retrospective observational study. The clinical criteria are women older than 50 years with symptoms related to large fibroids affecting their quality of life, who underwent UAE over a 4-year period at Royal Surrey Foundation Trust Hospital and London Clinic between 2012 and 2016. We retrieved the information from the patients' hospital notes and respective images, including magnetic resonance and ultrasound of the pelvis, and from questionnaires and telephone reviews. Main Outcome Measures: We measured the reduction of uterine size, complications, and overall satisfaction of patients. Results: The overall reduction of uterine size 8 weeks following UAE was between 50% and 64% in 12 out of 23 patients. Thirty-five percent of patients (8/23) experienced a reduction of over 65% of overall uterine volume. Only on 2 occasions, the reduction was below 50%. We asked the patients if they would recommend this operation. Twenty out of 23 would recommend it. Improvement of symptoms was measured with a scale between 0 and 5. Twelve out of 23 had total resolution of symptoms?no change in 1 case. One patient underwent a hysterectomy as symptoms persisted. Conclusions: In our series of women older than 50 years, UAE was an effective alternative to surgery, with reduction in fibroid size and improvement of symptoms.https://www.liebertpub.com/doi/full/10.1089/WHR.2021.0057uterine artery embolizationpostmenopausaluterine fibroids
spellingShingle Benedetto Mondelli
Woodruff John Walker
Tanveer Dhanoya
Karen Morton
Uterine Fibroid Embolization in a Series of Women Older Than 50 Years: An Observational Study
Women's Health Reports
uterine artery embolization
postmenopausal
uterine fibroids
title Uterine Fibroid Embolization in a Series of Women Older Than 50 Years: An Observational Study
title_full Uterine Fibroid Embolization in a Series of Women Older Than 50 Years: An Observational Study
title_fullStr Uterine Fibroid Embolization in a Series of Women Older Than 50 Years: An Observational Study
title_full_unstemmed Uterine Fibroid Embolization in a Series of Women Older Than 50 Years: An Observational Study
title_short Uterine Fibroid Embolization in a Series of Women Older Than 50 Years: An Observational Study
title_sort uterine fibroid embolization in a series of women older than 50 years an observational study
topic uterine artery embolization
postmenopausal
uterine fibroids
url https://www.liebertpub.com/doi/full/10.1089/WHR.2021.0057
work_keys_str_mv AT benedettomondelli uterinefibroidembolizationinaseriesofwomenolderthan50yearsanobservationalstudy
AT woodruffjohnwalker uterinefibroidembolizationinaseriesofwomenolderthan50yearsanobservationalstudy
AT tanveerdhanoya uterinefibroidembolizationinaseriesofwomenolderthan50yearsanobservationalstudy
AT karenmorton uterinefibroidembolizationinaseriesofwomenolderthan50yearsanobservationalstudy