The energy landscape analysis of cancer mutations in protein kinases.
The growing interest in quantifying the molecular basis of protein kinase activation and allosteric regulation by cancer mutations has fueled computational studies of allosteric signaling in protein kinases. In the present study, we combined computer simulations and the energy landscape analysis of...
Principais autores: | , |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
Public Library of Science (PLoS)
2011-01-01
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coleção: | PLoS ONE |
Acesso em linha: | http://europepmc.org/articles/PMC3188581?pdf=render |