Oligomerization and Nitration of the Grass Pollen Allergen Phl p 5 by Ozone, Nitrogen Dioxide, and Peroxynitrite: Reaction Products, Kinetics, and Health Effects

Oligomerization and Nitration of the Grass Pollen Allergen Phl p 5 by Ozone, Nitrogen Dioxide, and Peroxynitrite: Reaction Products, Kinetics, and Health Effects

The allergenic and inflammatory potential of proteins can be enhanced by chemical modification upon exposure to atmospheric or physiological oxidants. The molecular mechanisms and kinetics of such modifications, however, have not yet been fully resolved. We investigated the oligomerization and nitra...

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Bibliographic Details
Main Authors: Anna T. Backes, Kathrin Reinmuth-Selzle, Anna Lena Leifke, Kira Ziegler, Carola S. Krevert, Georg Tscheuschner, Kurt Lucas, Michael G. Weller, Thomas Berkemeier, Ulrich Pöschl, Janine Fröhlich-Nowoisky
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
tyrosine
nitrotyrosine
dityrosine
nitration degree
protein dimer
protein oligomer
Online Access:https://www.mdpi.com/1422-0067/22/14/7616

Internet

https://www.mdpi.com/1422-0067/22/14/7616

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