Treatment of insulinomas by laparoscopic radiofrequency ablation: case reports and literature review

Despite its rarity, insulinoma is the most common type of pancreatic endocrine neoplasm, with an occurrence of 1 to 5 per million per year in the population. Surgical resection or enucleation is the first line of curative treatment choice for insulinoma. Eight patients with symptomatic insulinomas t...

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Main Authors: Yao Changyu, Wang Xiangtao, Zhang Yongli, Kong Jian, Gao Jun, Ke Shan, Ding Xuemei, Xin Zonghai, Xu Wenlei, Wang Shaohong, Sun Wenbing
Format: Article
Language:English
Published: De Gruyter 2020-02-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2020-0013
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author Yao Changyu
Wang Xiangtao
Zhang Yongli
Kong Jian
Gao Jun
Ke Shan
Ding Xuemei
Xin Zonghai
Xu Wenlei
Wang Shaohong
Sun Wenbing
author_facet Yao Changyu
Wang Xiangtao
Zhang Yongli
Kong Jian
Gao Jun
Ke Shan
Ding Xuemei
Xin Zonghai
Xu Wenlei
Wang Shaohong
Sun Wenbing
author_sort Yao Changyu
collection DOAJ
description Despite its rarity, insulinoma is the most common type of pancreatic endocrine neoplasm, with an occurrence of 1 to 5 per million per year in the population. Surgical resection or enucleation is the first line of curative treatment choice for insulinoma. Eight patients with symptomatic insulinomas treated by radiofrequency ablation have been described since 2009. In the past two years, we treated two patients with symptomatic insulinomas (one in the pancreatic tail and the other in the pancreatic neck) successfully using laparoscopic radiofrequency ablation. Both patients achieved complete elimination without any significant complications. Our study suggests laparoscopic radiofrequency ablation could be developed as a safe and effective alternative treatment to surgery for the patients with insulinomas who refuse or are not eligible for surgery.
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spelling doaj.art-f8a2304c22fc4228966c297b534acdd72022-12-21T23:33:26ZengDe GruyterOpen Medicine2391-54632020-02-01151849110.1515/med-2020-0013med-2020-0013Treatment of insulinomas by laparoscopic radiofrequency ablation: case reports and literature reviewYao Changyu0Wang Xiangtao1Zhang Yongli2Kong Jian3Gao Jun4Ke Shan5Ding Xuemei6Xin Zonghai7Xu Wenlei8Wang Shaohong9Sun Wenbing10Department of Hepatobiliary Surgery, Beijing Chaoyang Hospital Affiliated to Capital Medical University, No. 5, Jingyuan Street, Beijing100043, ChinaDepartment of General Surgery, Zhanhua People’s Hospital, Shandong Province, ChinaDepartment of General Surgery, Zhanhua People’s Hospital, Shandong Province, ChinaDepartment of Hepatobiliary Surgery, Beijing Chaoyang Hospital Affiliated to Capital Medical University, No. 5, Jingyuan Street, Beijing100043, ChinaDepartment of Hepatobiliary Surgery, Beijing Chaoyang Hospital Affiliated to Capital Medical University, No. 5, Jingyuan Street, Beijing100043, ChinaDepartment of Hepatobiliary Surgery, Beijing Chaoyang Hospital Affiliated to Capital Medical University, No. 5, Jingyuan Street, Beijing100043, ChinaDepartment of Hepatobiliary Surgery, Beijing Chaoyang Hospital Affiliated to Capital Medical University, No. 5, Jingyuan Street, Beijing100043, ChinaDepartment of General Surgery, Zhanhua People’s Hospital, Shandong Province, ChinaDepartment of Hepatobiliary Surgery, Beijing Chaoyang Hospital Affiliated to Capital Medical University, No. 5, Jingyuan Street, Beijing100043, ChinaDepartment of Hepatobiliary Surgery, Beijing Chaoyang Hospital Affiliated to Capital Medical University, No. 5, Jingyuan Street, Beijing100043, ChinaDepartment of Hepatobiliary Surgery, Beijing Chaoyang Hospital Affiliated to Capital Medical University, No. 5, Jingyuan Street, Beijing100043, ChinaDespite its rarity, insulinoma is the most common type of pancreatic endocrine neoplasm, with an occurrence of 1 to 5 per million per year in the population. Surgical resection or enucleation is the first line of curative treatment choice for insulinoma. Eight patients with symptomatic insulinomas treated by radiofrequency ablation have been described since 2009. In the past two years, we treated two patients with symptomatic insulinomas (one in the pancreatic tail and the other in the pancreatic neck) successfully using laparoscopic radiofrequency ablation. Both patients achieved complete elimination without any significant complications. Our study suggests laparoscopic radiofrequency ablation could be developed as a safe and effective alternative treatment to surgery for the patients with insulinomas who refuse or are not eligible for surgery.https://doi.org/10.1515/med-2020-0013insulinomaradiofrequency ablationlaparoscopysafetyefficacy
spellingShingle Yao Changyu
Wang Xiangtao
Zhang Yongli
Kong Jian
Gao Jun
Ke Shan
Ding Xuemei
Xin Zonghai
Xu Wenlei
Wang Shaohong
Sun Wenbing
Treatment of insulinomas by laparoscopic radiofrequency ablation: case reports and literature review
Open Medicine
insulinoma
radiofrequency ablation
laparoscopy
safety
efficacy
title Treatment of insulinomas by laparoscopic radiofrequency ablation: case reports and literature review
title_full Treatment of insulinomas by laparoscopic radiofrequency ablation: case reports and literature review
title_fullStr Treatment of insulinomas by laparoscopic radiofrequency ablation: case reports and literature review
title_full_unstemmed Treatment of insulinomas by laparoscopic radiofrequency ablation: case reports and literature review
title_short Treatment of insulinomas by laparoscopic radiofrequency ablation: case reports and literature review
title_sort treatment of insulinomas by laparoscopic radiofrequency ablation case reports and literature review
topic insulinoma
radiofrequency ablation
laparoscopy
safety
efficacy
url https://doi.org/10.1515/med-2020-0013
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