Treatment of insulinomas by laparoscopic radiofrequency ablation: case reports and literature review
Despite its rarity, insulinoma is the most common type of pancreatic endocrine neoplasm, with an occurrence of 1 to 5 per million per year in the population. Surgical resection or enucleation is the first line of curative treatment choice for insulinoma. Eight patients with symptomatic insulinomas t...
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Format: | Article |
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De Gruyter
2020-02-01
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Series: | Open Medicine |
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Online Access: | https://doi.org/10.1515/med-2020-0013 |
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author | Yao Changyu Wang Xiangtao Zhang Yongli Kong Jian Gao Jun Ke Shan Ding Xuemei Xin Zonghai Xu Wenlei Wang Shaohong Sun Wenbing |
author_facet | Yao Changyu Wang Xiangtao Zhang Yongli Kong Jian Gao Jun Ke Shan Ding Xuemei Xin Zonghai Xu Wenlei Wang Shaohong Sun Wenbing |
author_sort | Yao Changyu |
collection | DOAJ |
description | Despite its rarity, insulinoma is the most common type of pancreatic endocrine neoplasm, with an occurrence of 1 to 5 per million per year in the population. Surgical resection or enucleation is the first line of curative treatment choice for insulinoma. Eight patients with symptomatic insulinomas treated by radiofrequency ablation have been described since 2009. In the past two years, we treated two patients with symptomatic insulinomas (one in the pancreatic tail and the other in the pancreatic neck) successfully using laparoscopic radiofrequency ablation. Both patients achieved complete elimination without any significant complications. Our study suggests laparoscopic radiofrequency ablation could be developed as a safe and effective alternative treatment to surgery for the patients with insulinomas who refuse or are not eligible for surgery. |
first_indexed | 2024-12-13T19:51:14Z |
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institution | Directory Open Access Journal |
issn | 2391-5463 |
language | English |
last_indexed | 2024-12-13T19:51:14Z |
publishDate | 2020-02-01 |
publisher | De Gruyter |
record_format | Article |
series | Open Medicine |
spelling | doaj.art-f8a2304c22fc4228966c297b534acdd72022-12-21T23:33:26ZengDe GruyterOpen Medicine2391-54632020-02-01151849110.1515/med-2020-0013med-2020-0013Treatment of insulinomas by laparoscopic radiofrequency ablation: case reports and literature reviewYao Changyu0Wang Xiangtao1Zhang Yongli2Kong Jian3Gao Jun4Ke Shan5Ding Xuemei6Xin Zonghai7Xu Wenlei8Wang Shaohong9Sun Wenbing10Department of Hepatobiliary Surgery, Beijing Chaoyang Hospital Affiliated to Capital Medical University, No. 5, Jingyuan Street, Beijing100043, ChinaDepartment of General Surgery, Zhanhua People’s Hospital, Shandong Province, ChinaDepartment of General Surgery, Zhanhua People’s Hospital, Shandong Province, ChinaDepartment of Hepatobiliary Surgery, Beijing Chaoyang Hospital Affiliated to Capital Medical University, No. 5, Jingyuan Street, Beijing100043, ChinaDepartment of Hepatobiliary Surgery, Beijing Chaoyang Hospital Affiliated to Capital Medical University, No. 5, Jingyuan Street, Beijing100043, ChinaDepartment of Hepatobiliary Surgery, Beijing Chaoyang Hospital Affiliated to Capital Medical University, No. 5, Jingyuan Street, Beijing100043, ChinaDepartment of Hepatobiliary Surgery, Beijing Chaoyang Hospital Affiliated to Capital Medical University, No. 5, Jingyuan Street, Beijing100043, ChinaDepartment of General Surgery, Zhanhua People’s Hospital, Shandong Province, ChinaDepartment of Hepatobiliary Surgery, Beijing Chaoyang Hospital Affiliated to Capital Medical University, No. 5, Jingyuan Street, Beijing100043, ChinaDepartment of Hepatobiliary Surgery, Beijing Chaoyang Hospital Affiliated to Capital Medical University, No. 5, Jingyuan Street, Beijing100043, ChinaDepartment of Hepatobiliary Surgery, Beijing Chaoyang Hospital Affiliated to Capital Medical University, No. 5, Jingyuan Street, Beijing100043, ChinaDespite its rarity, insulinoma is the most common type of pancreatic endocrine neoplasm, with an occurrence of 1 to 5 per million per year in the population. Surgical resection or enucleation is the first line of curative treatment choice for insulinoma. Eight patients with symptomatic insulinomas treated by radiofrequency ablation have been described since 2009. In the past two years, we treated two patients with symptomatic insulinomas (one in the pancreatic tail and the other in the pancreatic neck) successfully using laparoscopic radiofrequency ablation. Both patients achieved complete elimination without any significant complications. Our study suggests laparoscopic radiofrequency ablation could be developed as a safe and effective alternative treatment to surgery for the patients with insulinomas who refuse or are not eligible for surgery.https://doi.org/10.1515/med-2020-0013insulinomaradiofrequency ablationlaparoscopysafetyefficacy |
spellingShingle | Yao Changyu Wang Xiangtao Zhang Yongli Kong Jian Gao Jun Ke Shan Ding Xuemei Xin Zonghai Xu Wenlei Wang Shaohong Sun Wenbing Treatment of insulinomas by laparoscopic radiofrequency ablation: case reports and literature review Open Medicine insulinoma radiofrequency ablation laparoscopy safety efficacy |
title | Treatment of insulinomas by laparoscopic radiofrequency ablation: case reports and literature review |
title_full | Treatment of insulinomas by laparoscopic radiofrequency ablation: case reports and literature review |
title_fullStr | Treatment of insulinomas by laparoscopic radiofrequency ablation: case reports and literature review |
title_full_unstemmed | Treatment of insulinomas by laparoscopic radiofrequency ablation: case reports and literature review |
title_short | Treatment of insulinomas by laparoscopic radiofrequency ablation: case reports and literature review |
title_sort | treatment of insulinomas by laparoscopic radiofrequency ablation case reports and literature review |
topic | insulinoma radiofrequency ablation laparoscopy safety efficacy |
url | https://doi.org/10.1515/med-2020-0013 |
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