Spinal actions of lipoxin A4 and 17(R)-resolvin D1 attenuate inflammation-induced mechanical hypersensitivity and spinal TNF release.

Spinal actions of lipoxin A4 and 17(R)-resolvin D1 attenuate inflammation-induced mechanical hypersensitivity and spinal TNF release.

Lipoxins and resolvins have anti-inflammatory and pro-resolving actions and accumulating evidence indicates that these lipid mediators also attenuate pain-like behavior in a number of experimental models of inflammation and tissue injury-induced pain. The present study was undertaken to assess if sp...

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Bibliographic Details
Main Authors: Sally Abdelmoaty, Gustaf Wigerblad, Duygu B Bas, Simone Codeluppi, Teresa Fernandez-Zafra, El-Sayed El-Awady, Yasser Moustafa, Alaa El-Din S Abdelhamid, Ernst Brodin, Camilla I Svensson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3782447?pdf=render

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