COVID-19 and vaccination during pregnancy: a systematic analysis using Korea National Health Insurance claims data
Objective This study systematically analyzed coronavirus disease 2019 (COVID-19) and vaccination details during pregnancy by using the national health insurance claims data. Methods Population-based retrospective cohort data of 12,399,065 women aged 15–49 years were obtained from the Korea National...
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| Format: | Article |
| Language: | English |
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Korean Society of Obstetrics and Gynecology
2022-11-01
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| Series: | Obstetrics & Gynecology Science |
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| Online Access: | http://ogscience.org/upload/pdf/ogs-22060.pdf |
| _version_ | 1811179817095135232 |
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| author | Ki Hoon Ahn Hae-In Kim Kwang-Sig Lee Ju Sun Heo Ho-Yeon Kim Geum-Joon Cho Soon-Cheol Hong Min-Jeong Oh Hae-Joong Kim |
| author_facet | Ki Hoon Ahn Hae-In Kim Kwang-Sig Lee Ju Sun Heo Ho-Yeon Kim Geum-Joon Cho Soon-Cheol Hong Min-Jeong Oh Hae-Joong Kim |
| author_sort | Ki Hoon Ahn |
| collection | DOAJ |
| description | Objective This study systematically analyzed coronavirus disease 2019 (COVID-19) and vaccination details during pregnancy by using the national health insurance claims data. Methods Population-based retrospective cohort data of 12,399,065 women aged 15–49 years were obtained from the Korea National Health Insurance Service claims database between 2019 and 2021. Univariate analysis was performed to compare the obstetric outcomes of pregnant women (ICD-10 O00–O94) and their newborns (ICD-10 P00–P96) with and without COVID-19. Univariate analysis was also performed to compare the age and obstetric outcomes of pregnant women receiving different types of vaccines. Results The percentage of pregnant women with COVID-19 during pregnancy was 0.11%. Some obstetric outcomes of pregnant women with COVID-19, including the rates of preterm birth or cesarean delivery, were significantly better than those of pregnant women without COVID-19. The rate of miscarriage was higher in pregnant women with COVID-19 than without COVID-19. However, the outcomes of newborns of women with and without COVID-19 were not significantly different. Regarding vaccination type, obstetric outcomes of pregnant women appeared to be worse with the viral vector vaccine than with the mRNA vaccine. Conclusion To the best of our knowledge, this is the first study to systematically analyze COVID-19 and vaccination details during pregnancy using the national health insurance claims data in Korea. The obstetric outcomes in pregnant women with and without COVID-19 and their newborns were similar. |
| first_indexed | 2024-04-11T06:40:57Z |
| format | Article |
| id | doaj.art-f8ad592d5ac748e2a918a459cc024160 |
| institution | Directory Open Access Journal |
| issn | 2287-8572 2287-8580 |
| language | English |
| last_indexed | 2024-04-11T06:40:57Z |
| publishDate | 2022-11-01 |
| publisher | Korean Society of Obstetrics and Gynecology |
| record_format | Article |
| series | Obstetrics & Gynecology Science |
| spelling | doaj.art-f8ad592d5ac748e2a918a459cc0241602022-12-22T04:39:33ZengKorean Society of Obstetrics and GynecologyObstetrics & Gynecology Science2287-85722287-85802022-11-0165648750110.5468/ogs.220608716COVID-19 and vaccination during pregnancy: a systematic analysis using Korea National Health Insurance claims dataKi Hoon Ahn0Hae-In Kim1Kwang-Sig Lee2Ju Sun Heo3Ho-Yeon Kim4Geum-Joon Cho5Soon-Cheol Hong6Min-Jeong Oh7Hae-Joong Kim8 Department of Obstetrics and Gynecology, Korea University College of Medicine, Seoul, Korea Department of Obstetrics and Gynecology, Korea University College of Medicine, Seoul, Korea AI Center, Korea University Anam Hospital, Seoul, Korea Department of Pediatrics, Korea University College of Medicine, Seoul, Korea Department of Obstetrics and Gynecology, Korea University College of Medicine, Seoul, Korea Department of Obstetrics and Gynecology, Korea University College of Medicine, Seoul, Korea Department of Obstetrics and Gynecology, Korea University College of Medicine, Seoul, Korea Department of Obstetrics and Gynecology, Korea University College of Medicine, Seoul, Korea Department of Obstetrics and Gynecology, Korea University College of Medicine, Seoul, KoreaObjective This study systematically analyzed coronavirus disease 2019 (COVID-19) and vaccination details during pregnancy by using the national health insurance claims data. Methods Population-based retrospective cohort data of 12,399,065 women aged 15–49 years were obtained from the Korea National Health Insurance Service claims database between 2019 and 2021. Univariate analysis was performed to compare the obstetric outcomes of pregnant women (ICD-10 O00–O94) and their newborns (ICD-10 P00–P96) with and without COVID-19. Univariate analysis was also performed to compare the age and obstetric outcomes of pregnant women receiving different types of vaccines. Results The percentage of pregnant women with COVID-19 during pregnancy was 0.11%. Some obstetric outcomes of pregnant women with COVID-19, including the rates of preterm birth or cesarean delivery, were significantly better than those of pregnant women without COVID-19. The rate of miscarriage was higher in pregnant women with COVID-19 than without COVID-19. However, the outcomes of newborns of women with and without COVID-19 were not significantly different. Regarding vaccination type, obstetric outcomes of pregnant women appeared to be worse with the viral vector vaccine than with the mRNA vaccine. Conclusion To the best of our knowledge, this is the first study to systematically analyze COVID-19 and vaccination details during pregnancy using the national health insurance claims data in Korea. The obstetric outcomes in pregnant women with and without COVID-19 and their newborns were similar.http://ogscience.org/upload/pdf/ogs-22060.pdfcovid-19vaccinationpregnancyinfant, newbornpregnancy outcome |
| spellingShingle | Ki Hoon Ahn Hae-In Kim Kwang-Sig Lee Ju Sun Heo Ho-Yeon Kim Geum-Joon Cho Soon-Cheol Hong Min-Jeong Oh Hae-Joong Kim COVID-19 and vaccination during pregnancy: a systematic analysis using Korea National Health Insurance claims data Obstetrics & Gynecology Science covid-19 vaccination pregnancy infant, newborn pregnancy outcome |
| title | COVID-19 and vaccination during pregnancy: a systematic analysis using Korea National Health Insurance claims data |
| title_full | COVID-19 and vaccination during pregnancy: a systematic analysis using Korea National Health Insurance claims data |
| title_fullStr | COVID-19 and vaccination during pregnancy: a systematic analysis using Korea National Health Insurance claims data |
| title_full_unstemmed | COVID-19 and vaccination during pregnancy: a systematic analysis using Korea National Health Insurance claims data |
| title_short | COVID-19 and vaccination during pregnancy: a systematic analysis using Korea National Health Insurance claims data |
| title_sort | covid 19 and vaccination during pregnancy a systematic analysis using korea national health insurance claims data |
| topic | covid-19 vaccination pregnancy infant, newborn pregnancy outcome |
| url | http://ogscience.org/upload/pdf/ogs-22060.pdf |
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