Presumptive risk factors for monkeypox in rural communities in the Democratic Republic of the Congo.
Monkeypox virus (MPXV), a close relative of Variola virus, is a zoonotic virus with an unknown reservoir. Interaction with infected wildlife, bites from peri-domestic animals, and bushmeat hunting are hypothesized routes of infection from wildlife to humans. Using a Risk Questionnaire, performed in...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2017-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC5305065?pdf=render |
| _version_ | 1819030267671609344 |
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| author | Claire A Quiner Cynthia Moses Benjamin P Monroe Yoshinori Nakazawa Jeffrey B Doty Christine M Hughes Andrea M McCollum Saturnin Ibata Jean Malekani Emile Okitolonda Darin S Carroll Mary G Reynolds |
| author_facet | Claire A Quiner Cynthia Moses Benjamin P Monroe Yoshinori Nakazawa Jeffrey B Doty Christine M Hughes Andrea M McCollum Saturnin Ibata Jean Malekani Emile Okitolonda Darin S Carroll Mary G Reynolds |
| author_sort | Claire A Quiner |
| collection | DOAJ |
| description | Monkeypox virus (MPXV), a close relative of Variola virus, is a zoonotic virus with an unknown reservoir. Interaction with infected wildlife, bites from peri-domestic animals, and bushmeat hunting are hypothesized routes of infection from wildlife to humans. Using a Risk Questionnaire, performed in monkeypox-affected areas of rural Democratic Republic of the Congo, we describe the lifestyles and demographics associated with presumptive risk factors for MPXV infection. We generated two indices to assess risk: Household Materials Index (HMI), a proxy for socioeconomic status of households and Risk Activity Index (RAI), which describes presumptive risk for animal-to-human transmission of MPXV. Based on participant self-reported activity patterns, we found that people in this population are more likely to visit the forest than a market to fulfill material needs, and that the reported occupation is limited in describing behavior of individuals may participate. Being bitten by rodents in the home was commonly reported, and this was significantly associated with a low HMI. The highest scoring RAI sub-groups were 'hunters' and males aged ≥ 18 years; however, several activities involving MPXV-implicated animals were distributed across all sub-groups. The current analysis may be useful in identifying at-risk groups and help to direct education, outreach and prevention efforts more efficiently. |
| first_indexed | 2024-12-21T06:27:27Z |
| format | Article |
| id | doaj.art-f8afd11950dd4caab072427614496917 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-21T06:27:27Z |
| publishDate | 2017-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-f8afd11950dd4caab0724276144969172022-12-21T19:13:05ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01122e016866410.1371/journal.pone.0168664Presumptive risk factors for monkeypox in rural communities in the Democratic Republic of the Congo.Claire A QuinerCynthia MosesBenjamin P MonroeYoshinori NakazawaJeffrey B DotyChristine M HughesAndrea M McCollumSaturnin IbataJean MalekaniEmile OkitolondaDarin S CarrollMary G ReynoldsMonkeypox virus (MPXV), a close relative of Variola virus, is a zoonotic virus with an unknown reservoir. Interaction with infected wildlife, bites from peri-domestic animals, and bushmeat hunting are hypothesized routes of infection from wildlife to humans. Using a Risk Questionnaire, performed in monkeypox-affected areas of rural Democratic Republic of the Congo, we describe the lifestyles and demographics associated with presumptive risk factors for MPXV infection. We generated two indices to assess risk: Household Materials Index (HMI), a proxy for socioeconomic status of households and Risk Activity Index (RAI), which describes presumptive risk for animal-to-human transmission of MPXV. Based on participant self-reported activity patterns, we found that people in this population are more likely to visit the forest than a market to fulfill material needs, and that the reported occupation is limited in describing behavior of individuals may participate. Being bitten by rodents in the home was commonly reported, and this was significantly associated with a low HMI. The highest scoring RAI sub-groups were 'hunters' and males aged ≥ 18 years; however, several activities involving MPXV-implicated animals were distributed across all sub-groups. The current analysis may be useful in identifying at-risk groups and help to direct education, outreach and prevention efforts more efficiently.http://europepmc.org/articles/PMC5305065?pdf=render |
| spellingShingle | Claire A Quiner Cynthia Moses Benjamin P Monroe Yoshinori Nakazawa Jeffrey B Doty Christine M Hughes Andrea M McCollum Saturnin Ibata Jean Malekani Emile Okitolonda Darin S Carroll Mary G Reynolds Presumptive risk factors for monkeypox in rural communities in the Democratic Republic of the Congo. PLoS ONE |
| title | Presumptive risk factors for monkeypox in rural communities in the Democratic Republic of the Congo. |
| title_full | Presumptive risk factors for monkeypox in rural communities in the Democratic Republic of the Congo. |
| title_fullStr | Presumptive risk factors for monkeypox in rural communities in the Democratic Republic of the Congo. |
| title_full_unstemmed | Presumptive risk factors for monkeypox in rural communities in the Democratic Republic of the Congo. |
| title_short | Presumptive risk factors for monkeypox in rural communities in the Democratic Republic of the Congo. |
| title_sort | presumptive risk factors for monkeypox in rural communities in the democratic republic of the congo |
| url | http://europepmc.org/articles/PMC5305065?pdf=render |
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