Novel alterations in corneal neuroimmune phenotypes in mice with central nervous system tauopathy

Novel alterations in corneal neuroimmune phenotypes in mice with central nervous system tauopathy

Abstract Background Tauopathy in the central nervous system (CNS) is a histopathological hallmark of frontotemporal dementia (FTD) and Alzheimer’s disease (AD). Although AD is accompanied by various ocular changes, the effects of tauopathy on the integrity of the cornea, which is densely innervated...

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Bibliographic Details
Main Authors: Haihan Jiao, Laura E. Downie, Xin Huang, Mengliang Wu, Sara Oberrauch, Ryan J. Keenan, Laura H. Jacobson, Holly R. Chinnery
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Journal of Neuroinflammation
Subjects:
Central nervous system tauopathy
Immune cells
Cornea
Sensory nerves
Peripheral nervous system
Online Access:http://link.springer.com/article/10.1186/s12974-020-01803-7

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http://link.springer.com/article/10.1186/s12974-020-01803-7

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