Characterization of diverse populations of sinoatrial node cells and their proliferation potential at single nucleus resolutionResearch in context
Background: Each heartbeat is initiated in the sinoatrial node (SAN), and although a recent study (GSE130710) using single nucleus RNA-seq had discovered different populations of cell types within SAN tissue, the distinct potential functions of these cell types have not been delineated. Methods: To...
Main Authors: | Jia-Hua Qu, Richard Telljohann, Rostislav Byshkov, Edward G. Lakatta |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2023-01-01
|
Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844022039962 |
Similar Items
-
Transcriptome profile of the sinoatrial ring reveals conserved and novel genetic programs of the zebrafish pacemaker
by: Rashid Minhas, et al.
Published: (2021-10-01) -
Assembly of the Cardiac Pacemaking Complex: Electrogenic Principles of Sinoatrial Node Morphogenesis
by: Marietta Easterling, et al.
Published: (2021-04-01) -
Meaningful local signalling in sinoatrial node identified by random matrix theory and PCA
by: Chloe F Norris, et al.
Published: (2023-01-01) -
A novel conceptual model of heart rate autonomic modulation based on a small-world modular structure of the sinoatrial node
by: Alexander V. Maltsev, et al.
Published: (2023-12-01) -
Genetics of sinoatrial node function and heart rate disorders
by: Lieve E. van der Maarel, et al.
Published: (2023-05-01)