Tumour-Secreted Protein S (ProS1) Activates a Tyro3-Erk Signalling Axis and Protects Cancer Cells from Apoptosis

The TAM subfamily (Tyro3, Axl, MerTK) of receptor tyrosine kinases are implicated in several cancers, where they have been shown to support primary tumorigenesis as well as secondary resistance to cancer therapies. Relatively little is known about the oncogenic role of Tyro3, including its ligand se...

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Bibliographic Details
Main Authors: Nour Al Kafri, Sassan Hafizi
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/12/1843

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