An Adaptable, Portable Microarray Reader for Biodetection
We have developed an inexpensive portable microarray reader that can be applied to standard microscope slide-based arrays and other array formats printed on chemically modified surfaces. Measuring only 19 cm in length, the imaging device is portable and may be applicable to both triage and clinical...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2009-04-01
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| Series: | Sensors |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1424-8220/9/4/2524/ |
| _version_ | 1818040051256262656 |
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| author | Sebastian Wachsmann-Hogiu Matthew A. Coleman Joanna S. Albala Dennis Matthews Rupa Rao Cynthia Thomas Deanna L. Thompson Francesca Pearson |
| author_facet | Sebastian Wachsmann-Hogiu Matthew A. Coleman Joanna S. Albala Dennis Matthews Rupa Rao Cynthia Thomas Deanna L. Thompson Francesca Pearson |
| author_sort | Sebastian Wachsmann-Hogiu |
| collection | DOAJ |
| description | We have developed an inexpensive portable microarray reader that can be applied to standard microscope slide-based arrays and other array formats printed on chemically modified surfaces. Measuring only 19 cm in length, the imaging device is portable and may be applicable to both triage and clinical settings. For multiplexing and adaptability purposes, it can be modified to work with multiple excitation/emission wavelengths. Our device is shown to be comparable to a commercial laser scanner when detecting both streptavidin-biotin and antibody interactions. This paper presents the development and characterization of a handheld microarray imager and directly compares it with a commercial scanner. |
| first_indexed | 2024-12-10T08:08:23Z |
| format | Article |
| id | doaj.art-f8ba8fbd342642df889098718ab81740 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-12-10T08:08:23Z |
| publishDate | 2009-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-f8ba8fbd342642df889098718ab817402022-12-22T01:56:37ZengMDPI AGSensors1424-82202009-04-01942524253710.3390/s90402524An Adaptable, Portable Microarray Reader for BiodetectionSebastian Wachsmann-HogiuMatthew A. ColemanJoanna S. AlbalaDennis MatthewsRupa RaoCynthia ThomasDeanna L. ThompsonFrancesca PearsonWe have developed an inexpensive portable microarray reader that can be applied to standard microscope slide-based arrays and other array formats printed on chemically modified surfaces. Measuring only 19 cm in length, the imaging device is portable and may be applicable to both triage and clinical settings. For multiplexing and adaptability purposes, it can be modified to work with multiple excitation/emission wavelengths. Our device is shown to be comparable to a commercial laser scanner when detecting both streptavidin-biotin and antibody interactions. This paper presents the development and characterization of a handheld microarray imager and directly compares it with a commercial scanner.http://www.mdpi.com/1424-8220/9/4/2524/Microarraysimmunoassaysprotein arrayspoint-of-care diagnosticsportable microarray reader |
| spellingShingle | Sebastian Wachsmann-Hogiu Matthew A. Coleman Joanna S. Albala Dennis Matthews Rupa Rao Cynthia Thomas Deanna L. Thompson Francesca Pearson An Adaptable, Portable Microarray Reader for Biodetection Sensors Microarrays immunoassays protein arrays point-of-care diagnostics portable microarray reader |
| title | An Adaptable, Portable Microarray Reader for Biodetection |
| title_full | An Adaptable, Portable Microarray Reader for Biodetection |
| title_fullStr | An Adaptable, Portable Microarray Reader for Biodetection |
| title_full_unstemmed | An Adaptable, Portable Microarray Reader for Biodetection |
| title_short | An Adaptable, Portable Microarray Reader for Biodetection |
| title_sort | adaptable portable microarray reader for biodetection |
| topic | Microarrays immunoassays protein arrays point-of-care diagnostics portable microarray reader |
| url | http://www.mdpi.com/1424-8220/9/4/2524/ |
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