Dipeptidyl-peptidase-4 (DPP-4) inhibitor ameliorates 5-flurouracil induced intestinal mucositis

Dipeptidyl-peptidase-4 (DPP-4) inhibitor ameliorates 5-flurouracil induced intestinal mucositis

Abstract Background Chemotherapy-induced alimentary mucositis (AM) is difficult to prevent and treatment is rarely effective. Recent study have been showed that glucagon-like peptide (GLP)-1 and GLP-2 has protective in chemotherapy-induced AM. While the DPP-4 enzyme degrades this GLP-1, the DPP-4 in...

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Bibliographic Details
Main Authors: Jung Min Lee, In Kyung Yoo, Jae Min Lee, Seung Han Kim, Hyuk Soon Choi, Eun Sun Kim, Bora Keum, Yeon Seok Seo, Yoon Tae Jeen, Hoon Jai Chun, Hong Sik Lee, Soon Ho Um, Chang Duck Kim
Format: Article
Language:English
Published: BMC 2019-10-01
Series:BMC Cancer
Subjects:
Chemotherapy
Alimentary mucositis
Anti-inflammatory
Fluorouracil
Dipeptidyl-peptidase-4 inhibitor
Online Access:http://link.springer.com/article/10.1186/s12885-019-6231-y

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http://link.springer.com/article/10.1186/s12885-019-6231-y

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