Cardiometabolic Risk: Characteristics of the Intestinal Microbiome and the Role of Polyphenols
Cardiometabolic diseases like hypertension, type 2 diabetes mellitus, atherosclerosis, and obesity have been associated with changes in the gut microbiota structure, or dysbiosis. The beneficial effect of polyphenols on reducing the incidence of this chronic disease has been confirmed by numerous st...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-09-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/24/18/13757 |
| _version_ | 1797579777921515520 |
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| author | Ioana Mariana Haș Delia Mirela Tit Simona Gabriela Bungau Flavia Maria Pavel Bernadette-Emoke Teleky Dan Cristian Vodnar Cosmin Mihai Vesa |
| author_facet | Ioana Mariana Haș Delia Mirela Tit Simona Gabriela Bungau Flavia Maria Pavel Bernadette-Emoke Teleky Dan Cristian Vodnar Cosmin Mihai Vesa |
| author_sort | Ioana Mariana Haș |
| collection | DOAJ |
| description | Cardiometabolic diseases like hypertension, type 2 diabetes mellitus, atherosclerosis, and obesity have been associated with changes in the gut microbiota structure, or dysbiosis. The beneficial effect of polyphenols on reducing the incidence of this chronic disease has been confirmed by numerous studies. Polyphenols are primarily known for their anti-inflammatory and antioxidant properties, but they can also modify the gut microbiota. According to recent research, polyphenols positively influence the gut microbiota, which regulates metabolic responses and reduces systemic inflammation. This review emphasizes the prebiotic role of polyphenols and their impact on specific gut microbiota components in patients at cardiometabolic risk. It also analyzes the most recent research on the positive effects of polyphenols on cardiometabolic health. While numerous in vitro and in vivo studies have shown the interaction involving polyphenols and gut microbiota, additional clinical investigations are required to assess this effect in people. |
| first_indexed | 2024-03-10T22:41:47Z |
| format | Article |
| id | doaj.art-f8beba0b9568488db9a062dc73b4f3ee |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T22:41:47Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-f8beba0b9568488db9a062dc73b4f3ee2023-11-19T11:02:43ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-09-0124181375710.3390/ijms241813757Cardiometabolic Risk: Characteristics of the Intestinal Microbiome and the Role of PolyphenolsIoana Mariana Haș0Delia Mirela Tit1Simona Gabriela Bungau2Flavia Maria Pavel3Bernadette-Emoke Teleky4Dan Cristian Vodnar5Cosmin Mihai Vesa6Doctoral School of Biological and Biomedical Sciences, University of Oradea, 410087 Oradea, RomaniaDoctoral School of Biological and Biomedical Sciences, University of Oradea, 410087 Oradea, RomaniaDoctoral School of Biological and Biomedical Sciences, University of Oradea, 410087 Oradea, RomaniaDoctoral School of Biological and Biomedical Sciences, University of Oradea, 410087 Oradea, RomaniaInstitute of Life Sciences, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, RomaniaInstitute of Life Sciences, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, RomaniaDoctoral School of Biological and Biomedical Sciences, University of Oradea, 410087 Oradea, RomaniaCardiometabolic diseases like hypertension, type 2 diabetes mellitus, atherosclerosis, and obesity have been associated with changes in the gut microbiota structure, or dysbiosis. The beneficial effect of polyphenols on reducing the incidence of this chronic disease has been confirmed by numerous studies. Polyphenols are primarily known for their anti-inflammatory and antioxidant properties, but they can also modify the gut microbiota. According to recent research, polyphenols positively influence the gut microbiota, which regulates metabolic responses and reduces systemic inflammation. This review emphasizes the prebiotic role of polyphenols and their impact on specific gut microbiota components in patients at cardiometabolic risk. It also analyzes the most recent research on the positive effects of polyphenols on cardiometabolic health. While numerous in vitro and in vivo studies have shown the interaction involving polyphenols and gut microbiota, additional clinical investigations are required to assess this effect in people.https://www.mdpi.com/1422-0067/24/18/13757cardiometabolic riskgut microbiotamicrobiomepolyphenolsdysbiosisprebiotics |
| spellingShingle | Ioana Mariana Haș Delia Mirela Tit Simona Gabriela Bungau Flavia Maria Pavel Bernadette-Emoke Teleky Dan Cristian Vodnar Cosmin Mihai Vesa Cardiometabolic Risk: Characteristics of the Intestinal Microbiome and the Role of Polyphenols International Journal of Molecular Sciences cardiometabolic risk gut microbiota microbiome polyphenols dysbiosis prebiotics |
| title | Cardiometabolic Risk: Characteristics of the Intestinal Microbiome and the Role of Polyphenols |
| title_full | Cardiometabolic Risk: Characteristics of the Intestinal Microbiome and the Role of Polyphenols |
| title_fullStr | Cardiometabolic Risk: Characteristics of the Intestinal Microbiome and the Role of Polyphenols |
| title_full_unstemmed | Cardiometabolic Risk: Characteristics of the Intestinal Microbiome and the Role of Polyphenols |
| title_short | Cardiometabolic Risk: Characteristics of the Intestinal Microbiome and the Role of Polyphenols |
| title_sort | cardiometabolic risk characteristics of the intestinal microbiome and the role of polyphenols |
| topic | cardiometabolic risk gut microbiota microbiome polyphenols dysbiosis prebiotics |
| url | https://www.mdpi.com/1422-0067/24/18/13757 |
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