Very long intergenic non-coding (vlinc) RNAs directly regulate multiple genes in cis and trans

Very long intergenic non-coding (vlinc) RNAs directly regulate multiple genes in cis and trans

Abstract Background The majority of the human genome is transcribed in the form of long non-coding (lnc) RNAs. While these transcripts have attracted considerable interest, their molecular mechanisms of function and biological significance remain controversial. One of the main reasons behind this li...

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Bibliografiske detaljer
Main Authors: Huifen Cao, Dongyang Xu, Ye Cai, Xueer Han, Lu Tang, Fan Gao, Yao Qi, DingDing Cai, Huifang Wang, Maxim Ri, Denis Antonets, Yuri Vyatkin, Yue Chen, Xiang You, Fang Wang, Estelle Nicolas, Philipp Kapranov
Format: Article
Sprog:English
Udgivet: BMC 2021-05-01
Serier:BMC Biology
Fag:
lncRNA
vlincRNA
Regulatory networks
RNA-chromatin interactions
Single-molecule sequencing
CRISPR/Cas13
Online adgang:https://doi.org/10.1186/s12915-021-01044-x

Internet

https://doi.org/10.1186/s12915-021-01044-x

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