Managing reproductive problems in women with epilepsy of childbearing age

Abstract Girls and women constitute nearly 50% of all epilepsy cases. Apart from the disease symptoms, epilepsy and antiseizure medications (ASMs) may also affect the reproductive function, pregnancy and even the health of their offspring. Therefore, it is very important to identify and summarize th...

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Main Authors: Wanlin Lai, Shixu He, Dong Zhou, Lei Chen
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Acta Epileptologica
Subjects:
Online Access:https://doi.org/10.1186/s42494-021-00062-0
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author Wanlin Lai
Shixu He
Dong Zhou
Lei Chen
author_facet Wanlin Lai
Shixu He
Dong Zhou
Lei Chen
author_sort Wanlin Lai
collection DOAJ
description Abstract Girls and women constitute nearly 50% of all epilepsy cases. Apart from the disease symptoms, epilepsy and antiseizure medications (ASMs) may also affect the reproductive function, pregnancy and even the health of their offspring. Therefore, it is very important to identify and summarize the problems and risks for women with epilepsy (WWE) of childbearing age, and offer internationally recognized methods through multidisciplinary collaboration. In this review, we summarize the reproduction-related problems with WWE and propose multidisciplinary management by epileptologists, gynecologists and obstetricians, as well as other experts, from preconception to delivery. Large, multicenter registries are needed to advance our knowledge on new ASMs and their effects on WWE and their offspring.
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spelling doaj.art-f8c12d296514423e879b6d89ea44dd142022-12-21T19:10:42ZengBMCActa Epileptologica2524-44342021-11-013111010.1186/s42494-021-00062-0Managing reproductive problems in women with epilepsy of childbearing ageWanlin Lai0Shixu He1Dong Zhou2Lei Chen3Department of Neurology, West China Hospital, Sichuan UniversityDepartment of Neurology, West China Hospital, Sichuan UniversityDepartment of Neurology, West China Hospital, Sichuan UniversityDepartment of Neurology, West China Hospital, Sichuan UniversityAbstract Girls and women constitute nearly 50% of all epilepsy cases. Apart from the disease symptoms, epilepsy and antiseizure medications (ASMs) may also affect the reproductive function, pregnancy and even the health of their offspring. Therefore, it is very important to identify and summarize the problems and risks for women with epilepsy (WWE) of childbearing age, and offer internationally recognized methods through multidisciplinary collaboration. In this review, we summarize the reproduction-related problems with WWE and propose multidisciplinary management by epileptologists, gynecologists and obstetricians, as well as other experts, from preconception to delivery. Large, multicenter registries are needed to advance our knowledge on new ASMs and their effects on WWE and their offspring.https://doi.org/10.1186/s42494-021-00062-0Women with epilepsyReproductionAntiseizure medicationsTeratogenicityOffspringSeizure
spellingShingle Wanlin Lai
Shixu He
Dong Zhou
Lei Chen
Managing reproductive problems in women with epilepsy of childbearing age
Acta Epileptologica
Women with epilepsy
Reproduction
Antiseizure medications
Teratogenicity
Offspring
Seizure
title Managing reproductive problems in women with epilepsy of childbearing age
title_full Managing reproductive problems in women with epilepsy of childbearing age
title_fullStr Managing reproductive problems in women with epilepsy of childbearing age
title_full_unstemmed Managing reproductive problems in women with epilepsy of childbearing age
title_short Managing reproductive problems in women with epilepsy of childbearing age
title_sort managing reproductive problems in women with epilepsy of childbearing age
topic Women with epilepsy
Reproduction
Antiseizure medications
Teratogenicity
Offspring
Seizure
url https://doi.org/10.1186/s42494-021-00062-0
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