Dopamine-enabled anti-Hebbian timing-dependent plasticity in prefrontal circuitry

Dopamine-enabled anti-Hebbian timing-dependent plasticity in prefrontal circuitry

Spike timing-dependent plasticity (STDP) of glutamatergic synapses is a Hebbian associative plasticity that may underlie certain forms of learning. A cardinal feature of STDP is its dependence on the temporal order of presynaptic and postsynaptic spikes during induction: pre-post (positive) pairings...

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Bibliographic Details
Main Authors: Hongyu eRuan, Taixiang eSaur, Wei-Dong eYao
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Neural Circuits
Subjects:
Dopamine
Glutamate
Reward Learning
Hebbian
prefrontal cortex (PFC)
spike-timing dependent plasticity (STDP)
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncir.2014.00038/full

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