F0F1 ATP synthase regulates extracellular calcium influx in human neutrophils by interacting with Cav2.3 and modulates neutrophil accumulation in the lipopolysaccharide-challenged lung

F0F1 ATP synthase regulates extracellular calcium influx in human neutrophils by interacting with Cav2.3 and modulates neutrophil accumulation in the lipopolysaccharide-challenged lung

Abstract Background Neutrophils form the first line of innate host defense against invading microorganisms. We previously showed that F0F1 ATP synthase (F-ATPase), which is widely known as mitochondrial respiratory chain complex V, is expressed in the plasma membrane of human neutrophils and is invo...

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Bibliographic Details
Main Authors: Baoyi Zhu, Zhengfu Feng, Yan Guo, Tian Zhang, Ai Mai, Zhanfang Kang, Ting Weijen, Dai Wang, Dazhong Yin, Dongxing Zhu, Jun Gao
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Cell Communication and Signaling
Subjects:
F0F1 ATP synthase
Neutrophil
Voltage-gated calcium channel
Inflammation
Lung
Online Access:https://doi.org/10.1186/s12964-020-0515-3

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