A protocol for retrospective translational science case studies of health interventions
The critical processes driving successful research translation remain understudied. We describe a mixed-method case study protocol for analyzing translational research that has led to the successful development and implementation of innovative health interventions. An overarching goal of these case...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2021-01-01
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| Series: | Journal of Clinical and Translational Science |
| Subjects: | |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2059866120005142/type/journal_article |
| _version_ | 1811156615789805568 |
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| author | Sara E. Dodson Ira Kukic Linda Scholl Clara M. Pelfrey William M. Trochim |
| author_facet | Sara E. Dodson Ira Kukic Linda Scholl Clara M. Pelfrey William M. Trochim |
| author_sort | Sara E. Dodson |
| collection | DOAJ |
| description | The critical processes driving successful research translation remain understudied. We describe a mixed-method case study protocol for analyzing translational research that has led to the successful development and implementation of innovative health interventions. An overarching goal of these case studies is to describe systematically the chain of events between basic, fundamental scientific discoveries and the adoption of evidence-based health applications, including description of varied, long-term impacts. The case study approach isolates many of the key factors that enable the successful translation of research into practice and provides compelling evidence connecting the intervention to measurable changes in health and medical practice, public health outcomes, and other broader societal impacts. The goal of disseminating this protocol is to systematize a rigorous approach, which can enhance reproducibility, promote the development of a large collection of comparable studies, and enable cross-case analyses. This approach, an application of the “science of translational science,” will lead to a better understanding of key research process markers, timelines, and potential points of leverage for intervention that may help facilitate decisions, processes, and policies to speed the sustainable translational process. Case studies are effective communication vehicles to demonstrate both accountability and the impacts of the public’s investment in research. |
| first_indexed | 2024-04-10T04:54:19Z |
| format | Article |
| id | doaj.art-f8c38bbf59104a469175562238afd81b |
| institution | Directory Open Access Journal |
| issn | 2059-8661 |
| language | English |
| last_indexed | 2024-04-10T04:54:19Z |
| publishDate | 2021-01-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Journal of Clinical and Translational Science |
| spelling | doaj.art-f8c38bbf59104a469175562238afd81b2023-03-09T12:31:02ZengCambridge University PressJournal of Clinical and Translational Science2059-86612021-01-01510.1017/cts.2020.514A protocol for retrospective translational science case studies of health interventionsSara E. Dodson0Ira Kukic1Linda Scholl2Clara M. Pelfrey3https://orcid.org/0000-0002-6108-7555William M. Trochim4Office of Science Policy and Planning, National Institute of Neurological Diseases and Stroke, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USAOffice of Evaluation, Performance and Reporting, Division of Program Coordination, Planning, and Strategic Initiatives, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USAOffice of Applied Scholarship and Education Science, Mayo Clinic College of Medicine and Science, Rochester, MN, USAClinical and Translational Science Collaborative, Case Western Reserve University, Cleveland, OH, USAClinical and Translational Science Center, Weill Cornell Medicine, Cornell University, New York, NY, USAThe critical processes driving successful research translation remain understudied. We describe a mixed-method case study protocol for analyzing translational research that has led to the successful development and implementation of innovative health interventions. An overarching goal of these case studies is to describe systematically the chain of events between basic, fundamental scientific discoveries and the adoption of evidence-based health applications, including description of varied, long-term impacts. The case study approach isolates many of the key factors that enable the successful translation of research into practice and provides compelling evidence connecting the intervention to measurable changes in health and medical practice, public health outcomes, and other broader societal impacts. The goal of disseminating this protocol is to systematize a rigorous approach, which can enhance reproducibility, promote the development of a large collection of comparable studies, and enable cross-case analyses. This approach, an application of the “science of translational science,” will lead to a better understanding of key research process markers, timelines, and potential points of leverage for intervention that may help facilitate decisions, processes, and policies to speed the sustainable translational process. Case studies are effective communication vehicles to demonstrate both accountability and the impacts of the public’s investment in research.https://www.cambridge.org/core/product/identifier/S2059866120005142/type/journal_articleMixed-method case studyimpacttranslational research evaluationtranslational sciencehealth intervention |
| spellingShingle | Sara E. Dodson Ira Kukic Linda Scholl Clara M. Pelfrey William M. Trochim A protocol for retrospective translational science case studies of health interventions Journal of Clinical and Translational Science Mixed-method case study impact translational research evaluation translational science health intervention |
| title | A protocol for retrospective translational science case studies of health interventions |
| title_full | A protocol for retrospective translational science case studies of health interventions |
| title_fullStr | A protocol for retrospective translational science case studies of health interventions |
| title_full_unstemmed | A protocol for retrospective translational science case studies of health interventions |
| title_short | A protocol for retrospective translational science case studies of health interventions |
| title_sort | protocol for retrospective translational science case studies of health interventions |
| topic | Mixed-method case study impact translational research evaluation translational science health intervention |
| url | https://www.cambridge.org/core/product/identifier/S2059866120005142/type/journal_article |
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