Understanding Dissolution Rates via Continuous Flow Systems with Physiologically Relevant Metal Ion Saturation in Lysosome

Understanding Dissolution Rates via Continuous Flow Systems with Physiologically Relevant Metal Ion Saturation in Lysosome

Dissolution rates of nanomaterials can be decisive for acute in vivo toxicity (via the released ions) and for biopersistence (of the remaining particles). Continuous flow systems (CFSs) can screen for both aspects, but operational parameters need to be adjusted to the specific physiological compartm...

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Bibliographic Details
Main Authors: Johannes G. Keller, Willie Peijnenburg, Kai Werle, Robert Landsiedel, Wendel Wohlleben
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Nanomaterials
Subjects:
dissolution
dissolution rate
nanomaterial grouping
risk assessment
3r method
regulatory hazard assessment
Online Access:https://www.mdpi.com/2079-4991/10/2/311

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