Case report: Later onset of NRAS-mutant metastatic melanoma in a patient with a partially-excised giant congenital melanocytic nevus

Case report: Later onset of NRAS-mutant metastatic melanoma in a patient with a partially-excised giant congenital melanocytic nevus

Despite recent advances in treatment and surveillance, metastatic melanoma still carries a poor prognosis. Large/giant congenital melanocytic nevi (CMNs) constitute a known risk factor for the condition, with the greatest risk for malignant transformation thought to be during childhood (median age a...

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Bibliographic Details
Main Authors: Bruno Almeida Costa, Victor Zibara, Vasundhara Singh, Omid Hamid, Sonal Gandhi, Andrea P. Moy, Allison S. Betof Warner
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Medicine
Subjects:
metastatic melanoma
congenital melanocytic nevi
giant nevus
NRAS mutation
MDM2 amplification
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.1086473/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.1086473/full

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