MRI/PET multimodal imaging of the innate immune response in skeletal muscle and draining lymph node post vaccination in rats

MRI/PET multimodal imaging of the innate immune response in skeletal muscle and draining lymph node post vaccination in rats

The goal of this study was to utilize a multimodal magnetic resonance imaging (MRI) and positron emission tomography (PET) imaging approach to assess the local innate immune response in skeletal muscle and draining lymph node following vaccination in rats using two different vaccine platforms (AS01...

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Bibliographic Details
Main Authors: Saaussan Madi, Fang Xie, Kamyar Farhangi, Chih-Yang Hsu, Shih-Hsun Cheng, Tolulope Aweda, Bhasker Radaram, Stephanie Slania, Tammy Lambert, Mary Rambo, Tina Skedzielewski, Austin Cole, Valeriia Sherina, Shannon McKearnan, Hoang Tran, Hasan Alsaid, Minh Doan, Alan H. Stokes, Derek T. O’Hagan, Giulietta Maruggi, Sylvie Bertholet, Stéphane T. Temmerman, Russell Johnson, Beat M. Jucker
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
innate immune activation
magnetic resonance imaging
positron emission tomography
self-amplifying mRNA
lipid nanoparticle
AS01
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1081156/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1081156/full

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